2. GPCR/G Protein Anti-infection Neuronal Signaling Immunology/Inflammation Membrane Transporter/Ion Channel
  3. HCV TRP Channel Histamine Receptor
  4. Clemizole-d4

Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication.

For research use only. We do not sell to patients.

Clemizole-d<sub>4</sub> Chemical Structure

Clemizole-d4 Chemical Structure

Size Price Stock Quantity
1 mg USD 700 In-stock
5 mg USD 1750 In-stock
10 mg USD 2800 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Clemizole-d4 Related Antibodies

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Description

Clemizole-d4 is a deuterium labeled Clemizole. Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication[1].

Molecular Weight

329.86

Formula

C19H16D4ClN3
Appearance

Solid

Color

White to off-white

SMILES

ClC1=C([2H])C([2H])=C(C([2H])=C1[2H])CN2C(CN3CCCC3)=NC4=CC=CC=C24
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (303.16 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0316 mL 15.1579 mL 30.3159 mL
5 mM 0.6063 mL 3.0316 mL 6.0632 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0316 mL 15.1579 mL 30.3159 mL 75.7897 mL
5 mM 0.6063 mL 3.0316 mL 6.0632 mL 15.1579 mL
10 mM 0.3032 mL 1.5158 mL 3.0316 mL 7.5790 mL
15 mM 0.2021 mL 1.0105 mL 2.0211 mL 5.0526 mL
20 mM 0.1516 mL 0.7579 mL 1.5158 mL 3.7895 mL
25 mM 0.1213 mL 0.6063 mL 1.2126 mL 3.0316 mL
30 mM 0.1011 mL 0.5053 mL 1.0105 mL 2.5263 mL
40 mM 0.0758 mL 0.3789 mL 0.7579 mL 1.8947 mL
50 mM 0.0606 mL 0.3032 mL 0.6063 mL 1.5158 mL
60 mM 0.0505 mL 0.2526 mL 0.5053 mL 1.2632 mL
80 mM 0.0379 mL 0.1895 mL 0.3789 mL 0.9474 mL
100 mM 0.0303 mL 0.1516 mL 0.3032 mL 0.7579 mL
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Clemizole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clemizole-d4HCVTRP ChannelHistamine ReceptorHepatitis C virusTransient receptor potential channelsDeuteriumH1 histamine receptorHCV replicationInhibitorinhibitorinhibit

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