1. PROTAC
  2. PROTAC Linkers
  3. Folate-PEG3-C2-acid

Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.

For research use only. We do not sell to patients.

Folate-PEG3-C2-acid Chemical Structure

Folate-PEG3-C2-acid Chemical Structure

Size Price Stock Quantity
1 mg USD 450 In-stock
5 mg USD 950 In-stock
10 mg USD 1480 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.

Molecular Weight

644.63

Formula

C28H36N8O10

Appearance

Solid

Color

Light yellow to yellow

SMILES

NC(N1)=NC(N=CC(CNC2=CC=C(C(N[C@H](C(O)=O)CCC(NCCOCCOCCOCCC(O)=O)=O)=O)C=C2)=N3)=C3C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (51.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5513 mL 7.7564 mL 15.5128 mL
5 mM 0.3103 mL 1.5513 mL 3.1026 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5513 mL 7.7564 mL 15.5128 mL 38.7819 mL
5 mM 0.3103 mL 1.5513 mL 3.1026 mL 7.7564 mL
10 mM 0.1551 mL 0.7756 mL 1.5513 mL 3.8782 mL
15 mM 0.1034 mL 0.5171 mL 1.0342 mL 2.5855 mL
20 mM 0.0776 mL 0.3878 mL 0.7756 mL 1.9391 mL
25 mM 0.0621 mL 0.3103 mL 0.6205 mL 1.5513 mL
30 mM 0.0517 mL 0.2585 mL 0.5171 mL 1.2927 mL
40 mM 0.0388 mL 0.1939 mL 0.3878 mL 0.9695 mL
50 mM 0.0310 mL 0.1551 mL 0.3103 mL 0.7756 mL
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Folate-PEG3-C2-acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Folate-PEG3-C2-acid
Cat. No.:
HY-47373
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