ARPC3 - actin related protein 2/3 complex subunit 3 Gene

Homo sapiens

Also known as ARC21; p21-Arc

Gene ID: 10094 | Gene type: protein coding

About ARPC3

Cytogenetic location: 12q24.11 Genomic coordinates (GRCh38): 12:110,434,823-110,450,337 (from NCBI)

This gene has 9 transcripts (splice variants) and 222 orthologues. Ubiquitous expression in lymph node (RPKM 232.8), bone marrow (RPKM 231.9) and 25 other tissues.

Summary

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

ARPC3 Products(2)

mRNA	Protein	Name
NM_001287222.2	NP_001274151.1	actin-related protein 2/3 complex subunit 3 isoform 2
NM_001278556.2	NP_001265485.1	actin-related protein 2/3 complex subunit 3 isoform 1

ARPC3 Protein Structure

P21-Arc

0
100
178 a.a.

Protein Preferred Names

Protein Names

actin-related protein 2/3 complex subunit 3

ARP2/3 protein complex subunit p21	actin related protein 2/3 complex, subunit 3, 21kDa
arp2/3 complex 21 kDa subunit

Related Diseases

Diseases

Alias

Porokeratosis

Disseminated Superficial Actinic Porokeratosis	Dsap
Porokeratosis Of Mibelli	Porokeratosis, Disseminated Superficial Actinic
Porokeratosis, Disseminated Superficial Actinic, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS01018	ARPC3 Human Pre-designed siRNA Set A	/	Unkown
HY-RS01019	Arpc3 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS01020	Arpc3 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ARPC3	VGNC	VGNC:99890
Rattus norvegicus	ARPC3	RGD	RGD:1311985
Bos taurus	ARPC3	VGNC	VGNC:53890
Mus musculus	ARPC3	MGD	MGI:1928375

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