AP3S2 - adaptor related protein complex 3 subunit sigma 2 Gene

Homo sapiens

Also known as AP3S3; sigma3b

Gene ID: 10239 | Gene type: protein coding

About AP3S2

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:89,830,599-89,893,994 (from NCBI)

This gene has 16 transcripts (splice variants), 178 orthologues and 6 paralogues. Ubiquitous expression in kidney (RPKM 10.1), thyroid (RPKM 9.4) and 25 other tissues.

Summary

Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Located in intracellular membrane-bounded organelle. Part of AP-3 adaptor complex. [provided by Alliance of Genome Resources, Apr 2022]

AP3S2 Products(1)

mRNA	Protein	Name
NM_005829.5	NP_005820.1	AP-3 complex subunit sigma-2

AP3S2 Protein Structure

Clat_adaptor_s

0
100
193 a.a.

Protein Preferred Names

Protein Names

AP-3 complex subunit sigma-2

AP-3 complex subunit sigma-3B

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 48

DEE48	Epileptic Encephalopathy, Early Infantile, 48
Eiee48	Developmental And Epileptic Encephalopathy, 48
Early Infantile Epileptic Encephalopathy 48

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00795	AP3S2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	AP3S2	RGD	RGD:1586888
Bos taurus	AP3S2	VGNC	VGNC:53932
Felis catus	AP3S2	VGNC	VGNC:81041
Canis familiaris	AP3S2	VGNC	VGNC:50432
Mus musculus	AP3S2	MGD	MGI:1337060

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