2. Gene
  3. CCT8 - chaperonin containing TCP1 subunit 8 Gene

CCT8 - chaperonin containing TCP1 subunit 8 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Cctq; PRED71; D21S246; C21orf112

Gene ID: 10694 | Gene type: protein coding

About CCT8

Cytogenetic location: 21q21.3 Genomic coordinates (GRCh38): 21:29,056,326-29,073,648 (from NCBI)

This gene has 12 transcripts (splice variants), 212 orthologues and 13 paralogues. Ubiquitous expression in adrenal (RPKM 57.9), lymph node (RPKM 57.3) and 25 other tissues.

Summary

This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013]

CCT8 Products(4)

mRNA Protein Name
NM_001282907.2 NP_001269836.1 T-complex protein 1 subunit theta isoform 2
NM_001282908.2 NP_001269837.1 T-complex protein 1 subunit theta isoform 3
NM_001282909.2 NP_001269838.1 T-complex protein 1 subunit theta isoform 4
NM_006585.4 NP_006576.2 T-complex protein 1 subunit theta isoform 1

CCT8 Protein Structure

Cpn60_TCP1

Cpn60_TCP1: TCP-1/cpn60 chaperonin family (39 - 529)

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  • 548 a.a.
Protein Preferred Names Protein Names

T-complex protein 1 subunit theta

CCT-theta

Related Diseases

Diseases Alias
Otomycosis

Singapore Ear
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02185 CCT8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CCT8 VGNC VGNC:70749
Felis catus CCT8 VGNC VGNC:60582
Mus musculus CCT8 MGD MGI:107183
Canis familiaris CCT8 VGNC VGNC:38927
Rattus norvegicus CCT8 RGD RGD:1305452