SNX20 - sorting nexin 20 Gene

Homo sapiens

Also known as SLIC1

Gene ID: 124460 | Gene type: protein coding

About SNX20

Cytogenetic location: 16q12.1 Genomic coordinates (GRCh38): 16:50,666,300-50,681,312 (from NCBI)

This gene has 4 transcripts (splice variants), 186 orthologues and 1 paralogue. Biased expression in lymph node (RPKM 7.6), appendix (RPKM 6.3) and 12 other tissues.

Summary

SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.[supplied by OMIM, Feb 2010]

SNX20 Products(3)

mRNA	Protein	Name
NM_001144972.2	NP_001138444.1	sorting nexin-20 isoform 3
NM_153337.3	NP_699168.1	sorting nexin-20 isoform 2
NM_182854.4	NP_878274.1	sorting nexin-20 isoform 1

SNX20 Protein Structure

0
100
200
316 a.a.

Protein Preferred Names

Protein Names

sorting nexin-20

selectin ligand-interactor cytoplasmic 1

Related Diseases

Diseases

Alias

Immunodeficiency 73a With Defective Neutrophil Chemotaxis And Leukocytosis

Neutrophil Immunodeficiency Syndrome	IMD73A
Immunodeficiency 73a With Defective Neutrophil Chemotaxix And Leukocytosis	Immunodeficiency, Type 73a, With Defective Neutrophil Chemotaxix And Leukocytosis
Rac 2 Deficiency

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13534	SNX20 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SNX20	MGD	MGI:1918857
Felis catus	SNX20	VGNC	VGNC:65551
Macaca mulatta	SNX20	VGNC	VGNC:77796
Bos taurus	SNX20	VGNC	VGNC:35101
Canis familiaris	SNX20	VGNC	VGNC:46630
Rattus norvegicus	SNX20	RGD	RGD:1307787

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