2. Gene
  3. SLC43A2 - solute carrier family 43 member 2 Gene

SLC43A2 - solute carrier family 43 member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as LAT4

Gene ID: 124935 | Gene type: protein coding

About SLC43A2

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:1,569,254-1,630,088 (from NCBI)

This gene has 12 transcripts (splice variants), 1 gene allele, 283 orthologues and 1 paralogue. Broad expression in placenta (RPKM 24.5), kidney (RPKM 14.0) and 16 other tissues.

Summary

This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral Amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of Amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016]

SLC43A2 Products(5)

mRNA Protein Name
NM_001284498.2 NP_001271427.1 large neutral amino acids transporter small subunit 4 isoform 1
NM_001284499.1 NP_001271428.1 large neutral amino acids transporter small subunit 4 isoform 3
NM_001321364.2 NP_001308293.1 large neutral amino acids transporter small subunit 4 isoform 1
NM_001321365.2 NP_001308294.1 large neutral amino acids transporter small subunit 4 isoform 1
NM_152346.3 NP_689559.1 large neutral amino acids transporter small subunit 4 isoform 2

SLC43A2 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (87 - 387)

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  • 569 a.a.
Protein Preferred Names Protein Names

large neutral amino acids transporter small subunit 4

L-type amino acid transporter 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13249 SLC43A2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SLC43A2 RGD RGD:1305819
Mus musculus SLC43A2 MGD MGI:2442746
Macaca mulatta SLC43A2 VGNC VGNC:77554
Bos taurus SLC43A2 VGNC VGNC:34875
Felis catus SLC43A2 VGNC VGNC:65370
Canis familiaris SLC43A2 VGNC VGNC:46416