2. Gene
  3. UBE2F - ubiquitin conjugating enzyme E2 F (putative) Gene

UBE2F - ubiquitin conjugating enzyme E2 F (putative) Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NCE2

Gene ID: 140739 | Gene type: protein coding

About UBE2F

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:237,967,014-238,042,782 (from NCBI)

This gene has 23 transcripts (splice variants), 234 orthologues and 24 paralogues. Ubiquitous expression in bone marrow (RPKM 11.8), thyroid (RPKM 10.6) and 25 other tissues.

Summary

Enables NEDD8 conjugating Enzyme activity. Involved in protein neddylation. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

UBE2F Products(5)

mRNA Protein Name
NM_001278305.2 NP_001265234.1 NEDD8-conjugating enzyme UBE2F isoform 1
NM_001278306.2 NP_001265235.1 NEDD8-conjugating enzyme UBE2F isoform 2
NM_001278307.2 NP_001265236.1 NEDD8-conjugating enzyme UBE2F isoform 3
NM_001278308.2 NP_001265237.1 NEDD8-conjugating enzyme UBE2F isoform 4
NM_080678.3 NP_542409.1 NEDD8-conjugating enzyme UBE2F isoform 1

UBE2F Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (37 - 179)

  • 0
  • 100
  • 185 a.a.
Protein Preferred Names Protein Names

NEDD8-conjugating enzyme UBE2F

NEDD8 carrier protein UBE2F

Recombinant UBE2F Proteins

Cat. No. Product Name Accession Purity
HY-P76688 UBE2F Protein, Human (His) Q969M7 (M1-R185) ≥95%
HY-P79452 UBE2N/Ubc13 Protein, Human (sf9, His, Strep) P61088 (A2-I152) ≥95%

Related Diseases

Diseases Alias
Brachydactyly, Type E2

Brachydactyly Type E2

BDE2

Brachydactyly E2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15345 UBE2F Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus UBE2F VGNC VGNC:55693
Rattus norvegicus UBE2F RGD RGD:1307608
Felis catus UBE2F VGNC VGNC:80398
Mus musculus UBE2F MGD MGI:1915171
Canis familiaris UBE2F VGNC VGNC:59099
Macaca mulatta UBE2F VGNC VGNC:104562
Others UBE2F NCBI