MAGEB6 - MAGE family member B6 Gene

Homo sapiens

Also known as CT3.4; MAGE-B6; MAGEB6A

Gene ID: 158809 | Gene type: protein coding

About MAGEB6

Cytogenetic location: Xp21.3 Genomic coordinates (GRCh38): X:26,192,440-26,195,646 (from NCBI)

This gene has 1 transcript (splice variant), 232 orthologues and 37 paralogues. Restricted expression toward testis (RPKM 2.3).

Summary

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]

MAGEB6 Products(1)

mRNA	Protein	Name
NM_173523.2	NP_775794.2	melanoma-associated antigen B6

MAGEB6 Protein Structure

MAGE_N

MAGE

0
100
200
300
407 a.a.

Protein Preferred Names

Protein Names

melanoma-associated antigen B6

MAGE-B6 antigen

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 6

RP6	Retinitis Pigmentosa, X-Linked Recessive, 6
Retinitis Pigmentosa-6, X-Linked Recessive

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07972	MAGEB6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	MAGEB6	RGD	RGD:1565662

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