2. Gene
  3. EML5 - EMAP like 5 Gene

EML5 - EMAP like 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FAP16; EMAP-2; EMAP-5

Gene ID: 161436 | Gene type: protein coding

About EML5

Cytogenetic location: 14q31.3 Genomic coordinates (GRCh38): 14:88,612,431-88,792,953 (from NCBI)

This gene has 8 transcripts (splice variants), 201 orthologues and 9 paralogues. Biased expression in ovary (RPKM 10.1), prostate (RPKM 3.2) and 12 other tissues.

Summary

Predicted to enable microtubule binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

EML5 Products(4)

mRNA Protein Name
NM_001385116.1 NP_001372045.1 echinoderm microtubule-associated protein-like 5 isoform 2
NM_001385117.1 NP_001372046.1 echinoderm microtubule-associated protein-like 5 isoform 3
NM_001411033.1 NP_001397962.1 echinoderm microtubule-associated protein-like 5 isoform 4
NM_183387.3 NP_899243.1 echinoderm microtubule-associated protein-like 5 isoform 1

EML5 Protein Structure

HELP

HELP: HELP motif (3 - 48)

WD40

WD40: WD domain, G-beta repeat (104 - 135)

WD40

WD40: WD domain, G-beta repeat (235 - 263)

WD40

WD40: WD domain, G-beta repeat (325 - 353)

WD40

WD40: WD domain, G-beta repeat (557 - 592)

HELP

HELP: HELP motif (666 - 715)

WD40

WD40: WD domain, G-beta repeat (721 - 757)

WD40

WD40: WD domain, G-beta repeat (767 - 802)

WD40

WD40: WD domain, G-beta repeat (998 - 1026)

WD40

WD40: WD domain, G-beta repeat (1077 - 1109)

HELP

HELP: HELP motif (1350 - 1402)

WD40

WD40: WD domain, G-beta repeat (1695 - 1722)

WD40

WD40: WD domain, G-beta repeat (1929 - 1963)

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  • 1969 a.a.
Protein Preferred Names Protein Names

echinoderm microtubule-associated protein-like 5

echinoderm microtubule associated protein like 5

Related Diseases

Diseases Alias
Mucopolysaccharidosis, Type Ivb

Mucopolysaccharidosis Type Ivb

Mps Ivb

MPS4B

Morquio Syndrome B

Beta-D-Galactosidase Deficiency

Morquio Disease Type B

Mps 4b

Mucopolysaccharidosis Type 4b

Mpsivb

Morquio Disease, Type B

Mucopolysaccharidosis Type Iv-B

Mucopolysaccharidosis 4b

Morquio'S Syndrome B

Mps-Ivb
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04357 EML5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EML5 RGD RGD:1303275
Canis familiaris EML5 VGNC VGNC:40350
Bos taurus EML5 VGNC VGNC:28479
Mus musculus EML5 MGD MGI:2442513
Macaca mulatta EML5 VGNC VGNC:72067
Felis catus EML5 VGNC VGNC:80978