ADAL - adenosine deaminase like Gene

Homo sapiens

Also known as HsMAPDA

Gene ID: 161823 | Gene type: protein coding

About ADAL

Cytogenetic location: 15q15.3 Genomic coordinates (GRCh38): 15:43,330,351-43,354,569 (from NCBI)

This gene has 8 transcripts (splice variants), 203 orthologues and 2 paralogues. Broad expression in heart (RPKM 4.3), testis (RPKM 3.5) and 24 other tissues.

Summary

Predicted to enable Adenosine Deaminase activity. Predicted to be involved in adenosine catabolic process and inosine biosynthetic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

ADAL Products(7)

mRNA	Protein	Name
NM_001012969.4	NP_001012987.1	adenosine deaminase-like protein isoform 2
NM_001159280.3	NP_001152752.1	adenosine deaminase-like protein isoform 1
NM_001324364.2	NP_001311293.1	adenosine deaminase-like protein isoform 2
NM_001324365.2	NP_001311294.1	adenosine deaminase-like protein isoform 2
NM_001324366.2	NP_001311295.1	adenosine deaminase-like protein isoform 3
NM_001324367.2	NP_001311296.1	adenosine deaminase-like protein isoform 4
NM_001324368.2	NP_001311297.1	adenosine deaminase-like protein isoform 2

ADAL Protein Structure

A_deaminase

0
100
200
300
355 a.a.

Protein Preferred Names

Protein Names

adenosine deaminase-like protein

N6-mAMP deaminase

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 25

Developmental And Epileptic Encephalopathy, 25	Dee25
Developmental And Epileptic Encephalopathy 25, With Amelogenesis Imperfecta	Early Infantile Epileptic Encephalopathy 25
Encephalopathy, Epileptic, Early Infantile, Type 25

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00264	ADAL Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ADAL	RGD	RGD:1359517
Canis familiaris	ADAL	VGNC	VGNC:37572
Bos taurus	ADAL	VGNC	VGNC:25603
Felis catus	ADAL	VGNC	VGNC:59572
Mus musculus	ADAL	MGD	MGI:1923144
Macaca mulatta	ADAL	VGNC	VGNC:69555