P2rx1 - purinergic receptor P2X, ligand-gated ion channel, 1 Gene

Mus musculus

Also known as P2x; RP-2; Pdcd3

Gene ID: 18436 | Gene type: protein coding

About P2rx1

Chromosome 11: 72,889,929-72,906,026 forward strand.GRCm39:CM001004.3

This gene has 3 transcripts (splice variants), 199 orthologues, 6 paralogues and is associated with 5 phenotypes. Biased expression in bladder adult (RPKM 22.3) and thymus adult (RPKM 21.4).

Summary

Enables cation channel activity and purinergic nucleotide receptor activity. Acts upstream of or within several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of ion transport; and serotonin secretion by platelet. Located in external side of plasma membrane and postsynaptic membrane. Is expressed in several structures, including bladder; foregut-midgut junction; heart; liver lobe; and midgut. Orthologous to human P2RX1 (purinergic receptor P2X 1). [provided by Alliance of Genome Resources, Apr 2022]

P2rx1 Products(1)

mRNA	Protein	Name
NM_008771.3	NP_032797.3	P2X purinoceptor 1

P2rx1 Protein Structure

P2X

0
100
200
300
399 a.a.

Protein Preferred Names

Protein Names

P2X purinoceptor 1

ATP receptor	P2X1 receptor
programmed cell death 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09897	P2RX1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS09898	P2rx1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09899	P2rx1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2rx1	NCBI	NCBI:5023

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