KRT24 - keratin 24 Gene

Homo sapiens

Also known as K24; KA24; CK-24

Gene ID: 192666 | Gene type: protein coding

About KRT24

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:40,694,246-40,703,752 (from NCBI)

This gene has 1 transcript (splice variant), 114 orthologues and 68 paralogues. Biased expression in esophagus (RPKM 10.1), colon (RPKM 5.1) and 2 other tissues.

Summary

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the Cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jun 2009]

KRT24 Products(1)

mRNA	Protein	Name
NM_019016.3	NP_061889.2	keratin, type I cytoskeletal 24

KRT24 Protein Structure

Filament

0
100
200
300
400
525 a.a.

Protein Preferred Names

Protein Names

keratin, type I cytoskeletal 24

cytokeratin-24

Related Diseases

Diseases

Alias

Naegeli-Franceschetti-Jadassohn Syndrome

Naegeli Syndrome	Nfj Syndrome
NFJS	Reticular Skin Changes, Dental Anomalies, Decreased Function Of Sweat Glands, Strabismus, And Optic Atrophy
Naegeli-Franceschetti-Jadassohn Syndrome/Dermatopathia Pigmentosa Reticularis	Dpr
Franceschetti-Jadassohn Syndrome	Nfjs/Dpr

Retinitis Pigmentosa 42

RP42	Retinitis Pigmentosa-42
Retinitis Pigmentosa, Type 42

Dermatopathia Pigmentosa Reticularis

DPR

Ectodermal Dysplasia 4, Hair/Nail Type

Pure Hair And Nail Ectodermal Dysplasia	ECTD4
Ectodermal Dysplasia, Pure Hair-Nail Type	Ectodermal Dysplasia, 'Pure' Hair/Nail Type
Hned	Hair-Nail Ectodermal Dysplasia
Phned	Ectodermal Dysplasia Pure Hair-Nail Type
Ectodermal Dysplasia, 'Pure' Hair-Nail Type	Dysplasia, Ectodermal, Type 4, Hair/Nail

Brill-Zinsser Disease

Recrudescent Typhus	Brill Disease
Brill Zinsser Disease	Brill'S Disease
Latent Typhus	Sporadic Typhus
Typhus, Epidemic Louse-Borne	Recrudescent Typhus Due To Rickettsia Prowazekii
Recrudescent Typhus Fever	Recrudescent Brill-Zinsser Typhus Due To Rickettsia Prowazekii
Recrudescent Brill Disease	Recrudescent Typhus Fever Due To Rickettsia Prowazekii

Autosomal Dominant Severe Congenital Neutropenia

Severe Congenital Neutropenia Autosomal Dominant

Neutropenia, Congenital, Severe, Autosomal Dominant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07448	KRT24 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KRT24	RGD	RGD:1303157
Canis familiaris	KRT24	VGNC	VGNC:42523
Felis catus	KRT24	VGNC	VGNC:63170
Mus musculus	KRT24	MGD	MGI:1922956
Bos taurus	KRT24	VGNC	VGNC:30723
Macaca mulatta	KRT24	VGNC	VGNC:99164

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