APOBEC3F - apolipoprotein B mRNA editing enzyme catalytic subunit 3F Gene

Homo sapiens

Also known as A3F; KA6; ARP8; BK150C2.4.MRNA

Gene ID: 200316 | Gene type: protein coding

About APOBEC3F

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:39,040,864-39,055,972 (from NCBI)

This gene has 4 transcripts (splice variants), 52 orthologues and 9 paralogues. Broad expression in lymph node (RPKM 2.8), ovary (RPKM 2.8) and 24 other tissues.

Summary

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

APOBEC3F Products(2)

mRNA	Protein	Name
NM_001006666.2	NP_001006667.1	DNA dC->dU-editing enzyme APOBEC-3F isoform b
NM_145298.6	NP_660341.2	DNA dC->dU-editing enzyme APOBEC-3F isoform a

APOBEC3F Protein Structure

APOBEC_N

0
100
200
300
373 a.a.

Protein Preferred Names

Protein Names

DNA dC->dU-editing enzyme APOBEC-3F

apolipoprotein B editing enzyme catalytic polypeptide-like 3F

Related Diseases

Diseases

Alias

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency
Primary Immunodeficiency Disease	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00839	APOBEC3F Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-120157	Vif-ElonginC interaction inhibitor 1	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	APOBEC3F	MGD	MGI:1933111

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