2. Gene
  3. FRMPD1 - FERM and PDZ domain containing 1 Gene

FRMPD1 - FERM and PDZ domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FRMD2

Gene ID: 22844 | Gene type: protein coding

About FRMPD1

Cytogenetic location: 9p13.2 Genomic coordinates (GRCh38): 9:37,603,229-37,746,904 (from NCBI)

This gene has 3 transcripts (splice variants), 278 orthologues and 2 paralogues. Biased expression in testis (RPKM 3.6), skin (RPKM 1.1) and 2 other tissues.

Summary

Involved in establishment of protein localization to membrane and regulation of G protein-coupled receptor signaling pathway. Located in plasma membrane. Part of protein-containing complex. Colocalizes with cell cortex. [provided by Alliance of Genome Resources, Apr 2022]

FRMPD1 Products(4)

mRNA Protein Name
NM_001371223.1 NP_001358152.1 FERM and PDZ domain-containing protein 1
NM_001371224.1 NP_001358153.1 FERM and PDZ domain-containing protein 1
NM_001371225.1 NP_001358154.1 FERM and PDZ domain-containing protein 1
NM_014907.3 NP_055722.2 FERM and PDZ domain-containing protein 1

FRMPD1 Protein Structure

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (65 - 131)

FERM_N

FERM_N: FERM N-terminal domain (189 - 264)

FERM_M

FERM_M: FERM central domain (274 - 401)

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  • 1578 a.a.
Protein Preferred Names Protein Names

FERM and PDZ domain-containing protein 1

FERM domain-containing protein 2

Related Diseases

Diseases Alias
Intracranial Berry Aneurysm

Familial Aneurysmal Subarachnoid Hemorrhage

Familial Berry Aneurysm

Familial Intracranial Saccular Aneurysm

Saccular Cerebral Aneurysm

Aneurysm, Intracranial Berry

Aneurysmal Subarachnoid Hemorrhage

Aneurysm, Intracranial Berry, 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05107 FRMPD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FRMPD1 VGNC VGNC:52780
Felis catus FRMPD1 VGNC VGNC:62364
Rattus norvegicus FRMPD1 RGD RGD:1305229
Macaca mulatta FRMPD1 VGNC VGNC:72804
Mus musculus FRMPD1 MGD MGI:2446274
Canis familiaris FRMPD1 VGNC VGNC:51720