SBNO2 - strawberry notch homolog 2 Gene

Homo sapiens

Also known as SNO; STNO; KIAA0963

Gene ID: 22904 | Gene type: protein coding

About SBNO2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,107,638-1,174,268 (from NCBI)

This gene has 10 transcripts (splice variants), 1 gene allele, 215 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 17.5), spleen (RPKM 13.1) and 25 other tissues.

Summary

Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in several processes, including cellular response to interleukin-6; macrophage activation involved in immune response; and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SBNO2 Products(2)

mRNA	Protein	Name
NM_001100122.2	NP_001093592.1	protein strawberry notch homolog 2 isoform 2
NM_014963.3	NP_055778.2	protein strawberry notch homolog 2 isoform 1

SBNO2 Protein Structure

AAA_34

Helicase_C_4

0
300
600
900
1200
1366 a.a.

Protein Preferred Names

Protein Names

protein strawberry notch homolog 2

Related Diseases

Diseases

Alias

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12470	SBNO2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SBNO2	VGNC	VGNC:45885
Rattus norvegicus	SBNO2	RGD	RGD:1307194
Felis catus	SBNO2	VGNC	VGNC:82408
Mus musculus	SBNO2	MGD	MGI:2448490
Macaca mulatta	SBNO2	VGNC	VGNC:77123
Bos taurus	SBNO2	VGNC	VGNC:34309

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