EDC4 - enhancer of mRNA decapping 4 Gene

Homo sapiens

Also known as GE1; Ge-1; RCD8; HEDL5; HEDLS; RCD-8

Gene ID: 23644 | Gene type: protein coding

About EDC4

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,873,052-67,884,499 (from NCBI)

This gene has 14 transcripts (splice variants) and 212 orthologues. Ubiquitous expression in testis (RPKM 17.8), bone marrow (RPKM 15.0) and 25 other tissues.

Summary

Predicted to be involved in deadenylation-independent decapping of nuclear-transcribed mRNA. Located in P-body and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EDC4 Products(1)

mRNA	Protein	Name
NM_014329.5	NP_055144.3	enhancer of mRNA-decapping protein 4

Protein Preferred Names

Protein Names

enhancer of mRNA-decapping protein 4

autoantigen Ge-1

Related Diseases

Diseases

Alias

Human Granulocytic Anaplasmosis

Human Granulocytic Ehrlichiosis	Hge
Human Ehrlichial Infection, Human Granulocytic Type	Human Anaplasmosis Due To Anaplasma Phagocytophilum

Spherocytosis, Type 2

Hereditary Spherocytosis Type 2	SPH2
Spherocytosis, Hereditary, 2	Hs2
Hereditary Spherocytosis 2	Spherocytosis 2
Spherocytosis, Type 2, Autosomal Dominant

Ulnar Neuropathy

Ulnar Neuropathies

Thoracic Outlet Syndrome

Tos	Tos - Thoracic Outlet Syndrome
Thoracic Outlet Syndromes	Thoracic Outlet Compression Syndrome

Ehrlichiosis

Human Ehrlichiosis	He
Hey

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04156	EDC4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	EDC4	VGNC	VGNC:72058
Bos taurus	EDC4	VGNC	VGNC:28321
Felis catus	EDC4	VGNC	VGNC:61721
Mus musculus	EDC4	MGD	MGI:2446249
Rattus norvegicus	EDC4	RGD	RGD:1562009
Canis familiaris	EDC4	VGNC	VGNC:40193