1. Gene
  2. Ppard - peroxisome proliferator-activated receptor delta Gene

Ppard - peroxisome proliferator-activated receptor delta Gene

Rattus norvegicus

Also known as Pparb

Gene ID: 25682 | Gene type: protein coding

About Ppard

Primary_assembly 20: 6,298,785-6,363,968 forward strand.mRatBN7.2:CM026993.1

This gene has 2 transcripts (splice variants), 421 orthologues, 19 paralogues and is associated with 19 phenotypes. Biased expression in Heart (RPKM 3.7), Adrenal (RPKM 23.1) and 9 other tissues.

Summary

Enables NF-kappaB binding activity and fatty acid binding activity. Involved in several processes, including decidualization; negative regulation of collagen biosynthetic process; and positive regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Ppard Products(1)

mRNA Protein Name
NM_013141.2 NP_037273.2 peroxisome proliferator-activated receptor delta

Ppard Protein Structure

NR_DBD_Ppar

NR_DBD_Ppar: cd06965 (71 - 154)

NR_LBD_PPAR

NR_LBD_PPAR: cd06932 (171 - 438)

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  • 440 a.a.
Protein Preferred Names Protein Names

peroxisome proliferator-activated receptor delta

peroxisome proliferator activator receptor beta

peroxisome proliferator activator receptor, delta

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppard NCBI NCBI:5467