TPGS2 - tubulin polyglutamylase complex subunit 2 Gene

Homo sapiens

Also known as L17; PGs2; C18orf10; HMFN0601

Gene ID: 25941 | Gene type: protein coding

About TPGS2

This gene has 21 transcripts (splice variants) and 227 orthologues. Broad expression in testis (RPKM 16.4), brain (RPKM 5.6) and 24 other tissues.

Summary

This gene encodes a protein that is a component of the neuronal polyglutamylase complex, which plays a role in post-translational addition of glutamate residues to C-terminal tubulin tails. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]

TPGS2 Products(10)

mRNA	Protein	Name
NM_001271949.2	NP_001258878.1	tubulin polyglutamylase complex subunit 2 isoform 2
NM_001271950.2	NP_001258879.1	tubulin polyglutamylase complex subunit 2 isoform 3
NM_001271951.2	NP_001258880.1	tubulin polyglutamylase complex subunit 2 isoform 4
NM_001271952.2	NP_001258881.1	tubulin polyglutamylase complex subunit 2 isoform 5
NM_001271953.2	NP_001258882.1	tubulin polyglutamylase complex subunit 2 isoform 6
NM_001271954.2	NP_001258883.1	tubulin polyglutamylase complex subunit 2 isoform 7
NM_001271955.2	NP_001258884.1	tubulin polyglutamylase complex subunit 2 isoform 8
NM_001271956.2	NP_001258885.1	tubulin polyglutamylase complex subunit 2 isoform 9
NM_001330572.2	NP_001317501.1	tubulin polyglutamylase complex subunit 2 isoform 10
NM_015476.4	NP_056291.2	tubulin polyglutamylase complex subunit 2 isoform 1

Protein Preferred Names

Protein Names

tubulin polyglutamylase complex subunit 2

polyglutamylase subunit 2

Related Diseases

Diseases

Alias

Hypotrichosis 2

HYPT2	Hypotrichosis Simplex Of The Scalp 1
Htss1	Htss
Hypotrichosis, Spanish Type	Spanish Type Hypotrichosis
Hypotrichosis Spanish Type	Hypotrichosis, Type 2
Hypotrichosis Simplex Of Scalp

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14931	TPGS2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TPGS2	VGNC	VGNC:36248
Mus musculus	TPGS2	MGD	MGI:1913898
Canis familiaris	TPGS2	VGNC	VGNC:47737
Rattus norvegicus	TPGS2	RGD	RGD:1310571
Macaca mulatta	TPGS2	VGNC	VGNC:79442

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