2. Gene
  3. LSM14A - LSM14A mRNA processing body assembly factor Gene

LSM14A - LSM14A mRNA processing body assembly factor Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RAP55; FAM61A; RAP55A; C19orf13

Gene ID: 26065 | Gene type: protein coding

About LSM14A

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:34,172,504-34,229,288 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 245 orthologues, 1 paralogue and is associated with 62 phenotypes. Ubiquitous expression in thyroid (RPKM 23.9), lymph node (RPKM 21.2) and 25 other tissues.

Summary

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]

LSM14A Products(20)

mRNA Protein Name
NM_001114093.3 NP_001107565.1 protein LSM14 homolog A isoform a
NM_001384420.1 NP_001371349.1 protein LSM14 homolog A isoform c
NM_001384421.1 NP_001371350.1 protein LSM14 homolog A isoform d
NM_001384422.1 NP_001371351.1 protein LSM14 homolog A isoform e
NM_001384423.1 NP_001371352.1 protein LSM14 homolog A isoform f
NM_001384424.1 NP_001371353.1 protein LSM14 homolog A isoform g
NM_001384425.1 NP_001371354.1 protein LSM14 homolog A isoform h
NM_001384426.1 NP_001371355.1 protein LSM14 homolog A isoform i
NM_001384427.1 NP_001371356.1 protein LSM14 homolog A isoform j
NM_001384428.1 NP_001371357.1 protein LSM14 homolog A isoform k
NM_001384429.1 NP_001371358.1 protein LSM14 homolog A isoform l
NM_001384430.1 NP_001371359.1 protein LSM14 homolog A isoform m
NM_001384431.1 NP_001371360.1 protein LSM14 homolog A isoform n
NM_001384432.1 NP_001371361.1 protein LSM14 homolog A isoform o
NM_001384433.1 NP_001371362.1 protein LSM14 homolog A isoform o
NM_001384434.1 NP_001371363.1 protein LSM14 homolog A isoform o
NM_001384435.1 NP_001371364.1 protein LSM14 homolog A isoform p
NM_001384436.1 NP_001371365.1 protein LSM14 homolog A isoform q
NM_001384437.1 NP_001371366.1 protein LSM14 homolog A isoform r
NM_015578.4 NP_056393.2 protein LSM14 homolog A isoform b

LSM14A Protein Structure

LSM14

LSM14: Scd6-like Sm domain (4 - 97)

FDF

FDF: FDF domain (290 - 399)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 463 a.a.
Protein Preferred Names Protein Names

protein LSM14 homolog A

LSM14 homolog A

Related Diseases

Diseases Alias
Chromosome 19q13.11 Deletion Syndrome

19q13.11 Microdeletion Syndrome

Monosomy 19q13.11

Del(19)(Q13.11)
Spinal Cord Neuroblastoma

Neuroblastoma Of The Spinal Cord
Spinal Cord Primitive Neuroectodermal Neoplasm

Spinal Cord Pnet

Spinal Cord Primitive Neuroectodermal Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07856 LSM14A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LSM14A VGNC VGNC:42841
Macaca mulatta LSM14A VGNC VGNC:103832
Bos taurus LSM14A VGNC VGNC:31053
Mus musculus LSM14A MGD MGI:1914320
Felis catus LSM14A VGNC VGNC:63322
Rattus norvegicus LSM14A RGD RGD:1305695