AK5 - adenylate kinase 5 Gene

Homo sapiens

Also known as AK6

Gene ID: 26289 | Gene type: protein coding

About AK5

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:77,282,019-77,559,966 (from NCBI)

This gene has 13 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in brain (RPKM 40.3) and testis (RPKM 0.8).

Summary

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

AK5 Products(2)

mRNA	Protein	Name
NM_012093.4	NP_036225.2	adenylate kinase isoenzyme 5 isoform 2
NM_174858.3	NP_777283.1	adenylate kinase isoenzyme 5 isoform 1

AK5 Protein Structure

ADK

0
100
200
300
400
500
562 a.a.

Protein Preferred Names

Protein Names

adenylate kinase isoenzyme 5

AK 5

Related Diseases

Diseases

Alias

Limbic Encephalitis

Anterograde Amnesia

Amnesia, Anterograde

Chronic Frontal Sinusitis

Dissociative Amnesia

Psychogenic Amnesia	Amnesia, Dissociative
Amnesia, Psychogenic	Amnesia Neurosis
Hysterical Fugue	Dissociative Fugue

Transient Global Amnesia

Amnesia, Transient Global

Reticular Dysgenesis

Severe Combined Immunodeficiency With Leukopenia	De Vaal Disease
Congenital Aleukia	Aleukocytosis
Hematopoietic Hypoplasia, Generalized	Reticular Dysgenesia
Devaal Disease	Rd
Ak2 Deficiency	Congenital Aleukocytosis
Generalized Hematopoietic Hypoplasia	Scid With Leukopenia
RDYS

Connective Tissue Benign Neoplasm

Soft Tissue Neoplasms	Mesenchymal Tissue Neoplasm
Neoplasm Of Soft Tissue	Neoplasm Of Soft Tissues
Soft Tissue Benign Neoplasm	Tumor Of The Soft Tissue
Soft Tissue Neoplasm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00508	AK5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	AK5	VGNC	VGNC:37747
Rattus norvegicus	AK5	RGD	RGD:1590818
Macaca mulatta	AK5	VGNC	VGNC:69762
Bos taurus	AK5	VGNC	VGNC:25774
Felis catus	AK5	VGNC	VGNC:59707
Mus musculus	AK5	MGD	MGI:2677491
Others	AK5	NCBI