RND1 - Rho family GTPase 1 Gene

Homo sapiens

Also known as ARHS; RHO6; RHOS

Gene ID: 27289 | Gene type: protein coding

About RND1

Cytogenetic location: 12q13.12 Genomic coordinates (GRCh38): 12:48,857,145-48,865,870 (from NCBI)

This gene has 6 transcripts (splice variants), 261 orthologues and 22 paralogues. Biased expression in liver (RPKM 28.4), brain (RPKM 15.0) and 9 other tissues.

Summary

This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin Cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]

RND1 Products(1)

mRNA	Protein	Name
NM_014470.4	NP_055285.1	rho-related GTP-binding protein Rho6 precursor

RND1 Protein Structure

Ras

0
100
200
232 a.a.

Protein Preferred Names

Protein Names

rho-related GTP-binding protein Rho6

ras homolog gene family, member S

Related Diseases

Diseases

Alias

Ascaridiasis

Ascariasis

Deafness, Autosomal Recessive 104

DFNB104	Autosomal Recessive Nonsyndromic Deafness 104
Autosomal Recessive Deafness 104	Deafness, Autosomal Recessive, 104
Deafness, Autosomal Recessive, Type 104

Toxic Megacolon

Megacolon, Toxic	Toxic Dilatation Of Colon
Toxic Functional Megacolon

Clostridium Difficile Colitis

Pseudomembranous Colitis	Colitis Pseudomembranous
Enterocolitis, Pseudomembranous	Pseudomembranous Enterocolitis
Clostridium Difficile Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12031	RND1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RND1	VGNC	VGNC:45616
Felis catus	RND1	VGNC	VGNC:64661
Bos taurus	RND1	VGNC	VGNC:34004
Mus musculus	RND1	MGD	MGI:2444878
Rattus norvegicus	RND1	RGD	RGD:1306338
Macaca mulatta	RND1	VGNC	VGNC:100101