GML - glycosylphosphatidylinositol anchored molecule like Gene

Homo sapiens

Also known as LY6DL

Gene ID: 2765 | Gene type: protein coding

About GML

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,834,801-142,846,851 (from NCBI)

This gene has 2 transcripts (splice variants), 55 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Predicted to be involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; and negative regulation of cell population proliferation. Predicted to be extrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

GML Products(1)

mRNA	Protein	Name
NM_002066.3	NP_002057.1	glycosyl-phosphatidylinositol-anchored molecule-like protein precursor

Protein Preferred Names

Protein Names

glycosyl-phosphatidylinositol-anchored molecule-like protein

GPI anchored molecule like protein

Related Diseases

Diseases

Alias

Large Congenital Melanocytic Nevus

Giant Pigmented Hairy Nevus	Giant Congenital Melanocytic Nevus
Gmn	Congenital Pigmented Nevus
Lcmn	Gphn
Giant Congenital Nevus	Bathing Trunk Nevus
Congenital Giant Pigmented Nevus	Congenital Hairy Nevus
Giant Hairy Nevus	Giant Pigmented Nevus
Congenital Giant Pigmented Nevus Of Skin	Congenital Melanocytic Nevus Syndrome
Giant Congenital Melanocytic Nevi	Giant Congenital Pigmented Nevus
Melanocytic Nevus Syndrome, Congenital

Peroneal Nerve Paralysis

Peroneal Nerve Palsy

Cantu Syndrome

Hypertrichotic Osteochondrodysplasia	Hypertrichotic Osteochondrodysplasia Cantu Type
Cantú Syndrome	Craniofaciocardioskeletal Syndrome
Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome	Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum
Congenital Hypertrichosis-Coarse Facial Features Spectrum	HTOCD
Osteochondrodysplasia, Hypertrichotic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P1956	Human serum albumin	Inhibitor	≥99.0%	Unkown

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19805	STO-609	Inhibitor	98.13%	Unkown
HY-19805A	STO-609 acetate	Inhibitor	/	Unkown
HY-158401	Antibiofilm agent-7	Inhibitor	/	Unkown
HY-N9179	3′,4′,5′,5,6,7-Hexamethoxyflavone	Inhibitor	/	Unkown
HY-RS05521	GML Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GML	RGD	RGD:1307850
Macaca mulatta	GML	VGNC	VGNC:73081
Bos taurus	GML	VGNC	VGNC:29437

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