GNAZ - G protein subunit alpha z Gene

Homo sapiens

Also known as HG1H; gz-alpha

Gene ID: 2781 | Gene type: protein coding

About GNAZ

Cytogenetic location: 22q11.22-q11.23 Genomic coordinates (GRCh38): 22:23,070,519-23,125,032 (from NCBI)

This gene has 3 transcripts (splice variants), 211 orthologues and 15 paralogues. Broad expression in brain (RPKM 3.2), gall bladder (RPKM 1.3) and 16 other tissues.

Summary

The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]

GNAZ Products(1)

mRNA	Protein	Name
NM_002073.4	NP_002064.1	guanine nucleotide-binding protein G(z) subunit alpha

GNAZ Protein Structure

G-alpha

0
100
200
300
355 a.a.

Protein Preferred Names

Protein Names

guanine nucleotide-binding protein G(z) subunit alpha

g(x) alpha chain

Recombinant GNAZ Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72208	GNAZ Protein, Human (His-SUMO)	P19086 (G2-C355)	≥95%

Related Diseases

Diseases

Alias

Pertussis

Whooping Cough	Bordetella Infections
Bordetella Infection	Bordetella Pertussis Infection
Wc - Whooping Cough	Whooping Cough Due To Unspecified Organism
Bordetellosis	Tussis Convulsiva
Whooping Cough, Unspecified Organism	Wc - [Whooping Cough]
Whooping Cough Due To B. Parapertussis	Infection Due To Bordetella Parapertussis

Night Blindness

Nyctalopia

Thrombocytopenia-Absent Radius Syndrome

Tar Syndrome	Radial Aplasia-Thrombocytopenia Syndrome
Absent Radii And Thrombocytopenia	TAR
Chromosome 1q21.1 Deletion Syndrome, 200-Kb	Thrombocytopenia Absent Radius Syndrome
Thrombocytopenia Absent Radii	Chromosome 1q21.1 Deletion Syndrome
Thrombocytopenia With Absent Radii Syndrome	Radial Aplasia-Amegakaryocytic Thrombocytopenia

Achromatopsia

Achm	Rod Monochromatism
Total Color Blindness	Rod Monochromacy
Monochromatism	Achromatism
Complete Or Incomplete Color Blindness	Pingelapese Blindness
Achromatopsia 1	Achromatopsia 2
Achromatopsia 3

Ulna And Fibula, Absence Of, With Severe Limb Deficiency

Schinzel Phocomelia Syndrome	Aarrs
Limb/Pelvis-Hypoplasia/Aplasia Syndrome	LPHAS
Schinzel Type Phocomelia	Absence Of Ulna And Fibula With Severe Limb Deficiency
Al-Awadi/Raas-Rothschild Syndrome	Al Awadi-Raas-Rothschild Syndrome
Al-Awadi/Raas-Rothschild/Schinzel Phocomelia Syndrome	Aplasia/Hypoplasia Of Limbs And Pelvis
Congenital Absence Of Ulna And Fibula	Severe Limb Deficit
Phocomelia, Schinzel Type	Al-Awadi-Raas-Rothschild Syndrome
Ulna And Fibula Absence Of With Severe Limb Deficiency	Limb Pelvis Hypoplasia Aplasia Syndrome
Limb/Pelvis/Uterus-Hypoplasia/Aplasia Syndrome	Ulna And Fibula, Absence Of, With Sever Limb Deficiency

Pancreas, Annular

Annular Pancreas	Pancreas Annulare
Congenital Annular Pancreas

Usher Syndrome, Type Id

Usher Syndrome Type 1d	USH1D
Usher Syndrome, Type 1d	Usher Syndrome Type Id
Usher Syndrome, Type Id/F, Digenic	Usher Syndrome, Type 1d/F Digenic
Usher Syndrome 1d	Usher'S Syndrome Type 1d
Usher Syndrome 1d/F	USH1DF
Ush1d/F	Usher'S Syndrome Type 1h
Usher Syndrome 1h	Usher Syndrome Type Ih
Usher Syndrome, Type 1d/F

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05544	GNAZ Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GNAZ	RGD	RGD:2717
Bos taurus	GNAZ	VGNC	VGNC:58379
Canis familiaris	GNAZ	VGNC	VGNC:41310
Felis catus	GNAZ	VGNC	VGNC:62619
Macaca mulatta	GNAZ	VGNC	VGNC:73094
Mus musculus	GNAZ	MGD	MGI:95780
Others	GNAZ	NCBI