SLC25A6 - solute carrier family 25 member 6 Gene

Homo sapiens

Also known as ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y

Gene ID: 293 | Gene type: protein coding

About SLC25A6

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:1,386,152-1,392,113 (from NCBI)

This gene has 3 transcripts (splice variants), 124 orthologues and 49 paralogues. Ubiquitous expression in kidney (RPKM 238.9), ovary (RPKM 226.6) and 25 other tissues.

Summary

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce Apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]

SLC25A6 Products(1)

mRNA	Protein	Name
NM_001636.4	NP_001627.2	ADP/ATP translocase 3

SLC25A6 Protein Structure

Mito_carr

0
100
200
298 a.a.

Protein Preferred Names

Protein Names

ADP/ATP translocase 3

ADP,ATP carrier protein 3

Related Diseases

Diseases

Alias

Influenza

Flu	Influenza With Non-Respiratory Manifestation
Influenza With Other Manifestations	Influenza, Human
Influenza, Susceptibility To	Seasonal Influenza, Virus Identified

Bubonic Plague

Black Death	Plague, Bubonic
Plague, Septicemic	Pestis Bubonica

Plague

Yersiniosis	Yersinia Infections
Infection By Yersinia Pestis	Pasteurella Pestis Infection
Pestilential Fever	Yersinia Pestis Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13133	SLC25A6 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SLC25A6	VGNC	VGNC:49967
Canis familiaris	SLC25A6	VGNC	VGNC:54600
Rattus norvegicus	SLC25A6	RGD	RGD:1560896

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