2. Gene
  3. OBP2A - odorant binding protein 2A Gene

OBP2A - odorant binding protein 2A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as OBP; LCN13; OBP2C; OBPIIa; hOBPIIa

Gene ID: 29991 | Gene type: protein coding

About OBP2A

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:135,546,126-135,549,969 (from NCBI)

This gene has 7 transcripts (splice variants), 191 orthologues and 12 paralogues. Biased expression in testis (RPKM 2.5), skin (RPKM 0.2) and 1 other tissue.

Summary

This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport small, hydrophobic, volatile molecules or odorants through the nasal mucus to olfactory receptors, and may also function as a scavenger of highly concentrated or toxic odors. The protein is expressed as a monomer in the nasal mucus, and can bind diverse types of odorants with a higher affinity for aldehydes and fatty acids. This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

OBP2A Products(4)

mRNA Protein Name
NM_001293189.2 NP_001280118.1 odorant-binding protein 2a isoform gamma precursor
NM_001293193.2 NP_001280122.1 odorant-binding protein 2a isoform delta precursor
NM_001412135.1 NP_001399064.1 odorant-binding protein 2a isoform 5 precursor
NM_014582.3 NP_055397.1 odorant-binding protein 2a isoform alpha precursor

OBP2A Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (26 - 163)

  • 0
  • 100
  • 170 a.a.
Protein Preferred Names Protein Names

odorant-binding protein 2a

odorant-binding protein IIa

Related Diseases

Diseases Alias
Trombiculiasis
Syringomyelia

Hydromyelia
Vaginal Discharge
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09735 OBP2A Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus OBP2A RGD RGD:1588212