2. Gene
  3. Gpr183 - G protein-coupled receptor 183 Gene

Gpr183 - G protein-coupled receptor 183 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ebi2

Gene ID: 321019 | Gene type: protein coding

About Gpr183

Chromosome 14: 122,189,963-122,202,607 reverse strand.GRCm39:CM001007.3

This gene has 2 transcripts (splice variants), 207 orthologues, 5 paralogues and is associated with 12 phenotypes. Broad expression in spleen adult (RPKM 9.1), mammary gland adult (RPKM 4.9) and 15 other tissues.

Summary

Enables oxysterol binding activity. Involved in several processes, including dendritic cell homeostasis; leukocyte chemotaxis; and leukocyte differentiation. Acts upstream of or within leukocyte chemotaxis. Predicted to be located in plasma membrane. Is expressed in several structures, including Peyer's patch; central nervous system; genitourinary system; immune system; and intestine. Orthologous to human GPR183 (G protein-coupled receptor 183). [provided by Alliance of Genome Resources, Apr 2022]

Gpr183 Products(1)

mRNA Protein Name
NM_183031.2 NP_898852.2 G-protein coupled receptor 183

Gpr183 Protein Structure

7tmA_EBI2

7tmA_EBI2: cd15159 (27 - 314)

7tmA_EBI2

7tmA_EBI2: cd15159 (27 - 54)

7tmA_EBI2

7tmA_EBI2: cd15159 (61 - 86)

7tmA_EBI2

7tmA_EBI2: cd15159 (99 - 129)

7tmA_EBI2

7tmA_EBI2: cd15159 (141 - 163)

7tmA_EBI2

7tmA_EBI2: cd15159 (188 - 217)

7tmA_EBI2

7tmA_EBI2: cd15159 (232 - 262)

7tmA_EBI2

7tmA_EBI2: cd15159 (282 - 307)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 183

EBV-induced G-protein coupled receptor 2 homolog

Epstein-Barr virus induced gene 2

epstein-Barr virus-induced G-protein coupled receptor 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-113962 7α,25-Dihydroxycholesterol Agonist ≥99.0% Unkown
HY-147222 SAE-14 Antagonist 98.26% Unkown
HY-162011 GPR183 antagonist-2 Antagonist 99.96% Unkown
HY-113962S 7α,25-Dihydroxycholesterol-d6 / Unkown
HY-157939 GPR183 antagonist-3 Antagonist / Unkown
HY-RS05690 GPR183 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05691 Gpr183 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS05692 Gpr183 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-400897 7α,25-Dihydroxycholesterol intermediate-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr183 NCBI NCBI:1880