TAFA2 - TAFA chemokine like family member 2 Gene

Homo sapiens

Also known as TAFA-2; FAM19A2

Gene ID: 338811 | Gene type: protein coding

About TAFA2

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:61,708,273-62,260,034 (from NCBI)

This gene has 16 transcripts (splice variants), 126 orthologues and 3 paralogues. Biased expression in brain (RPKM 7.8), placenta (RPKM 1.2) and 5 other tissues.

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

TAFA2 Products(1)

mRNA	Protein	Name
NM_178539.5	NP_848634.1	chemokine-like protein TAFA-2 precursor

TAFA2 Protein Structure

TAFA

0
100
131 a.a.

Protein Preferred Names

Protein Names

chemokine-like protein TAFA-2

family with sequence similarity 19 (chemokine (C-C motif)-like), member A2

Recombinant TAFA2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71882	FAM19A2 Protein, Human	Q8N3H0 (A31-H131）	≥95%
HY-P72777	TAFA2/FAM19A2 Protein, Human	Q8N3H0 (A31-H131)	≥95%
HY-P77221	TAFA2/FAM19A2 Protein, Human (HEK293, Fc)	Q8N3H0 (A31-H131)	≥95%

Related Diseases

Diseases

Alias

Rumination Disorder

Rumination Syndrome	Psychogenic Rumination
Rumination Disorders

Char Syndrome

Patent Ductus Arteriosus With Facial Dysmorphism And Abnormal Fifth Digits

CHAR

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14180	TAFA2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TAFA2	VGNC	VGNC:78189
Felis catus	TAFA2	VGNC	VGNC:65939
Mus musculus	TAFA2	MGD	MGI:2143691
Canis familiaris	TAFA2	VGNC	VGNC:40647
Bos taurus	TAFA2	VGNC	VGNC:28778
Rattus norvegicus	TAFA2	RGD	RGD:1589429
Others	TAFA2	NCBI

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