ADAMTSL5 - ADAMTS like 5 Gene

Homo sapiens

Also known as THSD6

Gene ID: 339366 | Gene type: protein coding

About ADAMTSL5

This gene has 11 transcripts (splice variants), 188 orthologues and 25 paralogues. Broad expression in endometrium (RPKM 3.3), heart (RPKM 2.8) and 21 other tissues.

Summary

Enables heparin binding activity and microfibril binding activity. Located in extracellular region and microfibril. [provided by Alliance of Genome Resources, Apr 2022]

ADAMTSL5 Products(2)

mRNA	Protein	Name
NM_001367197.1	NP_001354126.1	ADAMTS-like protein 5 isoform 1 precursor
NM_213604.3	NP_998769.2	ADAMTS-like protein 5 isoform 2 precursor

ADAMTSL5 Protein Structure

TSP_1

ADAM_spacer1

NTR

0
100
200
300
400
471 a.a.

Protein Preferred Names

Protein Names

ADAMTS-like protein 5

ADAMTSL-5

Related Diseases

Diseases

Alias

Isolated Ectopia Lentis

Familial Ectopia Lentis	Ectopia Lentis
Ectopia Lentis Syndrome	Lens Subluxation
Iel	Congenital Ectopia Lentis
Subluxation Of Lens	Ectopia Lentis, Isolated
Ectopia Lentis Isolated

Autoimmune Lymphoproliferative Syndrome, Type Iii

ALPS3	Autoimmune Lymphoproliferative Syndrome Type 3
Immunodeficiency, Common Variable, 9, Formerly	Cvid9, Formerly
Autoimmune Lymphoproliferative Syndrome Type Iii	Autoimmune Lymphoproliferative Syndrome 3
Cvid9	Immunodeficiency, Common Variable, 9
Type 3 Autoimmune Lymphoproliferative Syndrome	Immunodeficiency, Variable, Common, Type 9

Peters-Plus Syndrome

Krause-Kivlin Syndrome	Peters Plus Syndrome
Peters Anomaly	Irido-Corneo-Trabecular Dysgenesis
PTRPLS	Peters Anomaly With Short-Limb Dwarfism
Peters Anomaly-Short Limb Dwarfism Syndrome	Peters Anomaly With Short Limb Dwarfism
Peters Congenital Glaucoma	Krause-Van Schooneveld-Kivlin Syndrome
Peters' Plus Syndrome	Peters'-Plus Syndrome
Anomaly Peters

Geleophysic Dysplasia

Geleophysic Dwarfism

Gphysd

Weill-Marchesani Syndrome

Gemss Syndrome	Spherophakia-Brachymorphia Syndrome
Marchesani-Weill Syndrome	Wms
Congenital Mesodermal Dystrophy	Mesodermal Dysmorphodystrophy, Congenital
Spherophakia Brachymorphia Syndrome	Mesodermal Dysmorphodystrophy Congenital
Wm Syndrome	Brachydactyly-Spherophakia Syndrome
Brachymorphy With Spherophakia Syndrome	Congenital Mesodermal Dysmorphodystrophy
Marchesani Syndrome	Weill-Marchesani Syndrome, Autosomal Recessive
Weill-Marchesani Syndrome, Autosomal Dominant

Acromicric Dysplasia

ACMICD	Acromicric Skeletal Dysplasia
Dysplasia, Acromicric

Winchester Syndrome

WNCHRS	Winchester Disease
Winchester-Grossman Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00314	ADAMTSL5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ADAMTSL5	RGD	RGD:1305607
Felis catus	ADAMTSL5	VGNC	VGNC:59603
Mus musculus	ADAMTSL5	MGD	MGI:1913798
Canis familiaris	ADAMTSL5	VGNC	VGNC:37609
Bos taurus	ADAMTSL5	VGNC	VGNC:106630
Macaca mulatta	ADAMTSL5	VGNC	VGNC:69540

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