TMEM150C - transmembrane protein 150C Gene

Homo sapiens

Also known as TTN3

Gene ID: 441027 | Gene type: protein coding

About TMEM150C

Cytogenetic location: 4q21.22 Genomic coordinates (GRCh38): 4:82,483,176-82,562,253 (from NCBI)

This gene has 4 transcripts (splice variants), 193 orthologues and 4 paralogues. Ubiquitous expression in ovary (RPKM 19.6), adrenal (RPKM 16.2) and 23 other tissues.

Summary

This gene encodes a transmembrane protein component of a mechanosensitve ion channel that is activated by mechanical stimuli in various cell types and confers slowly adapting, mechanically activated currents in dorsal root ganglion neurons. Mechanically activated ion channels are sensors that are critical for hearing, touch, pain, and blood pressure regulation. [provided by RefSeq, Jul 2017]

TMEM150C Products(3)

mRNA	Protein	Name
NM_001080506.3	NP_001073975.1	transmembrane protein 150C isoform 1
NM_001353454.2	NP_001340383.1	transmembrane protein 150C isoform 2
NM_001353455.2	NP_001340384.1	transmembrane protein 150C isoform 3

TMEM150C Protein Structure

Frag1

0
100
200
249 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 150C

tentonin 3

Related Diseases

Diseases

Alias

Malignant Hemangioma

Chromosome 4q21 Deletion Syndrome

4q21 Microdeletion Syndrome	Monosomy 4q21
Del(4)(Q21)	Chromosome Deletion Syndrome 4q21

Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema

Dehydrated Hereditary Stomatocytosis	Hereditary Xerocytosis
Xerocytosis, Hereditary	Pshk1
Pseudohyperkalemia Edinburgh	Dehydrated Hereditary Stomatocytosis With Or Without Pseudohyperkalemia And/Or Perinatal Edema
DHS1	Dhs
Hereditary Desiccytosis	Dehydrated Hereditary Stomatocytosis 1
Desiccytosis, Hereditary	Pseudohyperkalemia, Familial, 1, Due To Red Cell Leak
Pseudohyperkalemia Familial 1, Due To Red Cell Leak	Desiccytosis Hereditary
Xerocytosis Hereditary	Familial Pseudohyperkalemia 1 Due To Red Cell Leak
Stomatocytosis, Dehydrated, Hereditary, With/Without Pseudohyperkalemia And/Or Perinatal Edema	Xerocytosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14672	TMEM150C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TMEM150C	VGNC	VGNC:66284
Mus musculus	TMEM150C	MGD	MGI:3041258
Bos taurus	TMEM150C	VGNC	VGNC:35982
Rattus norvegicus	TMEM150C	RGD	RGD:1306105
Macaca mulatta	TMEM150C	VGNC	VGNC:100282
Canis familiaris	TMEM150C	VGNC	VGNC:47483

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