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  3. NFKBIL1 - NFKB inhibitor like 1 Gene

NFKBIL1 - NFKB inhibitor like 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IKBL; NFKBIL

Gene ID: 4795 | Gene type: protein coding

About NFKBIL1

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,546,851-31,558,829 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 181 orthologues and is associated with 1 phenotype. Ubiquitous expression in ovary (RPKM 7.9), fat (RPKM 7.6) and 25 other tissues.

Summary

This gene encodes a divergent member of the I-kappa-B family of proteins. Its function has not been determined. The gene lies within the major histocompatibility complex (MHC) class I region on chromosome 6. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]

NFKBIL1 Products(4)

mRNA Protein Name
NM_001144961.2 NP_001138433.1 NF-kappa-B inhibitor-like protein 1 isoform 2
NM_001144962.2 NP_001138434.1 NF-kappa-B inhibitor-like protein 1 isoform 3
NM_001144963.2 NP_001138435.1 NF-kappa-B inhibitor-like protein 1 isoform 4
NM_005007.4 NP_004998.3 NF-kappa-B inhibitor-like protein 1 isoform 1

NFKBIL1 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (49 - 110)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
Protein Preferred Names Protein Names

NF-kappa-B inhibitor-like protein 1

I-kappa-B-like protein

Related Diseases

Diseases Alias
Rheumatoid Arthritis

RA

Arthritis, Rheumatoid

Rheumatoid Arthritis, Susceptibility To

Arthritis Or Polyarthritis, Rheumatic

Atrophic Arthritis

Rheumatism Arthritis

Rheumatoid Polyarthritis
Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09264 NFKBIL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NFKBIL1 VGNC VGNC:68487
Canis familiaris NFKBIL1 VGNC VGNC:43784
Bos taurus NFKBIL1 VGNC VGNC:32049
Mus musculus NFKBIL1 MGD MGI:1340031
Rattus norvegicus NFKBIL1 RGD RGD:1303310
Macaca mulatta NFKBIL1 VGNC VGNC:104414