1. Gene
  2. SDF4 - stromal cell derived factor 4 Gene

SDF4 - stromal cell derived factor 4 Gene

Homo sapiens

Also known as Cab45; SDF-4

Gene ID: 51150 | Gene type: protein coding

About SDF4

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,216,931-1,232,001 (from NCBI)

This gene has 7 transcripts (splice variants), 200 orthologues and 4 paralogues. Ubiquitous expression in colon (RPKM 31.3), kidney (RPKM 26.5) and 25 other tissues.

Summary

This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]

SDF4 Products(2)

mRNA Protein Name
NM_016176.6 NP_057260.3 45 kDa calcium-binding protein isoform 2 precursor
NM_016547.3 NP_057631.2 45 kDa calcium-binding protein isoform 1 precursor

SDF4 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (103 - 163)

EF-hand_5

EF-hand_5: EF hand (287 - 305)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
Protein Preferred Names Protein Names

45 kDa calcium-binding protein

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Diseases Alias
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Waldenstroem'S Macroglobulinemia

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Macroglobulinemia Of Waldenstrom

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Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

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Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SDF4 RGD RGD:621521
Bos taurus SDF4 VGNC VGNC:34387
Macaca mulatta SDF4 VGNC VGNC:77092
Felis catus SDF4 VGNC VGNC:64949
Mus musculus SDF4 MGD MGI:108079
Canis familiaris SDF4 VGNC VGNC:45948