2. Gene
  3. COPZ2 - COPI coat complex subunit zeta 2 Gene

COPZ2 - COPI coat complex subunit zeta 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as zeta2-COP

Gene ID: 51226 | Gene type: protein coding

About COPZ2

Cytogenetic location: 17q21.32 Genomic coordinates (GRCh38): 17:48,026,167-48,048,053 (from NCBI)

This gene has 10 transcripts (splice variants), 192 orthologues and 1 paralogue. Broad expression in fat (RPKM 13.1), prostate (RPKM 4.4) and 22 other tissues.

Summary

This gene encodes a member of the adaptor complexes small subunit family. The encoded protein is a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. [provided by RefSeq, Feb 2014]

COPZ2 Products(1)

mRNA Protein Name
NM_016429.4 NP_057513.1 coatomer subunit zeta-2

COPZ2 Protein Structure

Clat_adaptor_s

Clat_adaptor_s: Clathrin adaptor complex small chain (43 - 180)

  • 0
  • 100
  • 208 a.a.
Protein Preferred Names Protein Names

coatomer subunit zeta-2

coatomer protein complex subunit zeta 2

Related Diseases

Diseases Alias
Penis Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Penis

Epidermoid Cell Carcinoma Of Penis

Squamous Cell Carcinoma Of The Penis

Penile Squamous Cell Carcinoma
Intellectual Developmental Disorder, Autosomal Dominant 56

Mental Retardation, Autosomal Dominant 56

MRD56

Autosomal Dominant Mental Retardation 56

Autosomal Dominant Intellectual Developmental Disorder 56

Autosomal Dominant Intellectual Developmental Disorder-56
Developmental And Epileptic Encephalopathy 48

DEE48

Epileptic Encephalopathy, Early Infantile, 48

Eiee48

Developmental And Epileptic Encephalopathy, 48

Early Infantile Epileptic Encephalopathy 48
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03035 COPZ2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus COPZ2 VGNC VGNC:98889
Canis familiaris COPZ2 VGNC VGNC:39515
Rattus norvegicus COPZ2 RGD RGD:1306948
Macaca mulatta COPZ2 VGNC VGNC:71220
Bos taurus COPZ2 VGNC VGNC:27608
Mus musculus COPZ2 MGD MGI:1929008