NGRN - neugrin, neurite outgrowth associated Gene

Homo sapiens

Also known as DSC92

Gene ID: 51335 | Gene type: protein coding

About NGRN

Cytogenetic location: 15q26.1 Genomic coordinates (GRCh38): 15:90,265,663-90,272,211 (from NCBI)

This gene has 3 transcripts (splice variants) and 168 orthologues. Ubiquitous expression in brain (RPKM 111.2), prostate (RPKM 60.9) and 25 other tissues.

Summary

Enables rRNA binding activity. Involved in positive regulation of mitochondrial translation. Located in several cellular components, including intercellular bridge; mitotic spindle; and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

NGRN Products(1)

mRNA	Protein	Name
NM_001033088.3	NP_001028260.2	neugrin precursor

NGRN Protein Structure

Neugrin

0
100
200
291 a.a.

Protein Preferred Names

Protein Names

neugrin

mesenchymal stem cell protein DSC92

Related Diseases

Diseases

Alias

Deafness, Autosomal Dominant 16

DFNA16	Autosomal Dominant Nonsyndromic Deafness 16
Autosomal Dominant Deafness 16

Deafness, Autosomal Dominant 18

DFNA18	Autosomal Dominant Nonsyndromic Deafness 18
Autosomal Dominant Deafness 18

Deafness, Autosomal Recessive 27

DFNB27	Autosomal Recessive Nonsyndromic Deafness 27
Autosomal Recessive Deafness 27

Deafness, Autosomal Dominant 27

DFNA27	Autosomal Dominant Nonsyndromic Deafness 27
Autosomal Dominant Deafness 27	Deafness, Autosomal Dominant, 27

Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome

Jacobs Syndrome	Arthropathy-Camptodactyly Syndrome
Pericarditis-Arthropathy-Camptodactyly Syndrome	Xyy Syndrome
Pac Syndrome	Cacp Syndrome
CACP	Fibrosing Serositis, Familial
Camptodactyly-Arthropathy-Pericarditis Syndrome	Cap Syndrome
47, Xyy Syndrome	47,Xyy Syndrome
Double Y Syndrome	Camptodactyly-Arthropathy-Coxa-Vara-Pericarditis Syndrome
Hypertrophic Synovitis, Congenital Familial	Congenital Familial Hypertrophic Synovitis
Xyy Karyotype	Y Disomy
Yy Syndrome	Familial Fibrosing Serositis
Disomy Y	Double Y
Camptodactyly Arthropathy Coxa Vara Pericarditis Syndrome	Arthropathy Camptodactyly Syndrome
Camptodactyly Arthropathy Pericarditis Syndrome	Pericarditis Arthropathy Camptodactyly Syndrome
Jacob'S Syndrome	47,Xyy
Cdags Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09280	NGRN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NGRN	MGD	MGI:1933212
Felis catus	NGRN	VGNC	VGNC:80900
Rattus norvegicus	NGRN	RGD	RGD:1583734
Bos taurus	NGRN	VGNC	VGNC:57159
Canis familiaris	NGRN	VGNC	VGNC:59024