1. Gene
  2. SNX7 - sorting nexin 7 Gene

SNX7 - sorting nexin 7 Gene

Homo sapiens
Gene ID: 51375 | Gene type: protein coding

About SNX7

Cytogenetic location: 1p21.3 Genomic coordinates (GRCh38): 1:98,661,319-98,760,500 (from NCBI)

This gene has 5 transcripts (splice variants), 208 orthologues and 15 paralogues. Ubiquitous expression in colon (RPKM 10.6), small intestine (RPKM 8.3) and 24 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jun 2010]

SNX7 Products(3)

mRNA Protein Name
NM_001364903.1 NP_001351832.1 sorting nexin-7 isoform c
NM_015976.5 NP_057060.2 sorting nexin-7 isoform a
NM_152238.4 NP_689424.2 sorting nexin-7 isoform b

SNX7 Protein Structure

PX

PX: PX domain (99 - 210)

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  • 451 a.a.
Protein Preferred Names Protein Names

sorting nexin-7

Orthologs Information

Species Symbol Source ID
Felis catus SNX7 VGNC VGNC:80362
Rattus norvegicus SNX7 RGD RGD:1305480
Canis familiaris SNX7 VGNC VGNC:46643
Bos taurus SNX7 VGNC VGNC:35113
Mus musculus SNX7 MGD MGI:1923811
Macaca mulatta SNX7 VGNC VGNC:106500