2. Gene
  3. IP6K2 - inositol hexakisphosphate kinase 2 Gene

IP6K2 - inositol hexakisphosphate kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PIUS; IHPK2; InsP6K2

Gene ID: 51447 | Gene type: protein coding

About IP6K2

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:48,688,003-48,717,221 (from NCBI)

This gene has 28 transcripts (splice variants), 267 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 16.6), skin (RPKM 16.3) and 25 other tissues.

Summary

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

IP6K2 Products(8)

mRNA Protein Name
NM_001005909.3 NP_001005909.1 inositol hexakisphosphate kinase 2 isoform a
NM_001005910.3 NP_001005910.1 inositol hexakisphosphate kinase 2 isoform b
NM_001005911.3 NP_001005911.1 inositol hexakisphosphate kinase 2 isoform b
NM_001146178.3 NP_001139650.1 inositol hexakisphosphate kinase 2 isoform c
NM_001146179.3 NP_001139651.1 inositol hexakisphosphate kinase 2 isoform c
NM_001190316.2 NP_001177245.1 inositol hexakisphosphate kinase 2 isoform d
NM_001190317.2 NP_001177246.1 inositol hexakisphosphate kinase 2 isoform e
NM_016291.4 NP_057375.2 inositol hexakisphosphate kinase 2 isoform a

IP6K2 Protein Structure

IPK

IPK: Inositol polyphosphate kinase (203 - 417)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 426 a.a.
Protein Preferred Names Protein Names

inositol hexakisphosphate kinase 2

ATP:1D-myo-inositol-hexakisphosphate phosphotransferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150607 UNC7467 98.07% Unkown
HY-122706 TBK1/IKKε-IN-3 / Unkown
HY-153530 LI-2242 / Unkown
HY-RS06862 IP6K2 Human Pre-designed siRNA Set A / Unkown
HY-161032 IP6K2-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus IP6K2 VGNC VGNC:62952
Mus musculus IP6K2 MGD MGI:1923750
Macaca mulatta IP6K2 VGNC VGNC:73612
Rattus norvegicus IP6K2 RGD RGD:620529
Canis familiaris IP6K2 VGNC VGNC:42062
Bos taurus IP6K2 VGNC VGNC:30238