SERPINB10 - serpin family B member 10 Gene

Homo sapiens

Also known as PI10; PI-10

Gene ID: 5273 | Gene type: protein coding

About SERPINB10

Cytogenetic location: 18q22.1 Genomic coordinates (GRCh38): 18:63,907,958-63,936,111 (from NCBI)

This gene has 1 transcript (splice variant), 122 orthologues and 36 paralogues. Restricted expression toward bone marrow (RPKM 23.0).

Summary

This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate Cancer. [provided by RefSeq, Dec 2015]

SERPINB10 Products(1)

mRNA	Protein	Name
NM_005024.3	NP_005015.1	serpin B10

SERPINB10 Protein Structure

Serpin

0
100
200
300
397 a.a.

Protein Preferred Names

Protein Names

serpin B10

bomapin

Related Diseases

Diseases

Alias

Tracheal Calcification

Calcification Of Trachea

Chronic Myelomonocytic Leukemia

Leukemia, Myelomonocytic, Chronic	Cmml
Leukemia Myelomonocytic Chronic	Cmml - [Chronic Myelomonocytic Leukaemia]
Chronic Myelomonocytic Leukaemia Without Mention Of Remission	Chronic Monocytic Leukaemia
Chronic Monocytoid Leukaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12706	SERPINB10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SERPINB10	RGD	RGD:628853
Canis familiaris	SERPINB10	VGNC	VGNC:46027
Felis catus	SERPINB10	VGNC	VGNC:68833
Mus musculus	SERPINB10	MGD	MGI:2138648
Macaca mulatta	SERPINB10	VGNC	VGNC:77365
Bos taurus	SERPINB10	VGNC	VGNC:56372
Others	SERPINB10	NCBI

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