CLIC6 - chloride intracellular channel 6 Gene

Homo sapiens

Also known as CLIC1L

Gene ID: 54102 | Gene type: protein coding

About CLIC6

Cytogenetic location: 21q22.12 Genomic coordinates (GRCh38): 21:34,668,994-34,718,223 (from NCBI)

This gene has 2 transcripts (splice variants), 223 orthologues and 14 paralogues. Biased expression in stomach (RPKM 24.4), thyroid (RPKM 6.8) and 10 other tissues.

Summary

This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2015]

CLIC6 Products(2)

mRNA	Protein	Name
NM_001317009.2	NP_001303938.1	chloride intracellular channel protein 6 isoform 1
NM_053277.3	NP_444507.1	chloride intracellular channel protein 6 isoform 2

CLIC6 Protein Structure

GST_N_3

GST_C_2

0
200
400
600
704 a.a.

Protein Preferred Names

Protein Names

chloride intracellular channel protein 6

chloride channel form A

Related Diseases

Diseases

Alias

Deafness, Autosomal Recessive 103

DFNB103	Autosomal Recessive Nonsyndromic Deafness 103
Autosomal Recessive Deafness 103	Deafness, Autosomal Recessive, 103
Deafness, Autosomal Recessive, Type 103

Retinitis Pigmentosa 20

RP20	Retinitis Pigmentosa, Type 20

Retinitis Pigmentosa 25

RP25	Retinitis Pigmentosa-25
Retinitis Pigmentosa, Type 25

Deafness, Autosomal Recessive 102

DFNB102	Autosomal Recessive Nonsyndromic Deafness 102
Autosomal Recessive Deafness 102	Deafness, Autosomal Recessive, 102
Deafness, Autosomal Recessive, Type 102

Ischemic Neuropathy

Ischemic Peripheral Neuropathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02808	CLIC6 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CLIC6	VGNC	VGNC:53024
Felis catus	CLIC6	VGNC	VGNC:102674
Mus musculus	CLIC6	MGD	MGI:2146607
Rattus norvegicus	CLIC6	RGD	RGD:727938
Macaca mulatta	CLIC6	VGNC	VGNC:71256

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