2. Gene
  3. ERRFI1 - ERBB receptor feedback inhibitor 1 Gene

ERRFI1 - ERBB receptor feedback inhibitor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MIG6; RALT; MIG-6; GENE-33

Gene ID: 54206 | Gene type: protein coding

About ERRFI1

Cytogenetic location: 1p36.23 Genomic coordinates (GRCh38): 1:8,011,727-8,026,309 (from NCBI)

This gene has 5 transcripts (splice variants) and 259 orthologues. Broad expression in liver (RPKM 123.7), gall bladder (RPKM 60.1) and 20 other tissues.

Summary

ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]

ERRFI1 Products(1)

mRNA Protein Name
NM_018948.4 NP_061821.1 ERBB receptor feedback inhibitor 1

ERRFI1 Protein Structure

GTPase_binding

GTPase_binding: GTPase binding (4 - 68)

Inhibitor_Mig-6

Inhibitor_Mig-6: EGFR receptor inhibitor Mig-6 (315 - 371)

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  • 462 a.a.
Protein Preferred Names Protein Names

ERBB receptor feedback inhibitor 1

mitogen-inducible gene 6 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04516 ERRFI1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ERRFI1 VGNC VGNC:28598
Macaca mulatta ERRFI1 VGNC VGNC:99913
Rattus norvegicus ERRFI1 RGD RGD:1307599
Mus musculus ERRFI1 MGD MGI:1921405
Canis familiaris ERRFI1 VGNC VGNC:40469
Felis catus ERRFI1 VGNC VGNC:61958