MIOS - meiosis regulator for oocyte development Gene

Homo sapiens

Also known as MIO; Sea4; Yulink

Gene ID: 54468 | Gene type: protein coding

About MIOS

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:7,566,884-7,609,144 (from NCBI)

This gene has 9 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in prostate (RPKM 7.9), testis (RPKM 7.5) and 25 other tissues.

Summary

Involved in cellular response to amino acid starvation; positive regulation of TOR signaling; and protein-containing complex localization. Located in several cellular components, including cytosol; lysosomal membrane; and nucleoplasm. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2022]

MIOS Products(5)

mRNA	Protein	Name
NM_001370076.1	NP_001357005.1	GATOR complex protein MIOS isoform 1
NM_001370077.1	NP_001357006.1	GATOR complex protein MIOS isoform 1
NM_001370078.1	NP_001357007.1	GATOR complex protein MIOS isoform 2
NM_001370080.1	NP_001357009.1	GATOR complex protein MIOS isoform 1
NM_019005.4	NP_061878.3	GATOR complex protein MIOS isoform 1

Protein Preferred Names

Protein Names

GATOR complex protein MIOS

H_DJ1159O04.1

Related Diseases

Diseases

Alias

Trichothiodystrophy 6, Nonphotosensitive

TTD6	Nonphotosensitive Trichothiodystrophy 6
Trichothiodystrophy 6, Non-Photosensitive

Nonphotosensitive Trichothiodystrophy

Trichothiodystrophy Nonphotosensitive

Amish Brittle Hair Brain Syndrome

Sarcocystosis

Sarcosporidiosis

Sarcosporidiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08458	MIOS Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MIOS	VGNC	VGNC:63514
Macaca mulatta	MIOS	VGNC	VGNC:74804
Canis familiaris	MIOS	VGNC	VGNC:43239
Bos taurus	MIOS	VGNC	VGNC:31481
Rattus norvegicus	MIOS	RGD	RGD:1308432
Mus musculus	MIOS	MGD	MGI:2182066