2. Gene
  3. SPATA6 - spermatogenesis associated 6 Gene

SPATA6 - spermatogenesis associated 6 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HASH; SRF1; SRF-1

Gene ID: 54558 | Gene type: protein coding

About SPATA6

Cytogenetic location: 1p33 Genomic coordinates (GRCh38): 1:48,261,389-48,472,204 (from NCBI)

This gene has 11 transcripts (splice variants), 143 orthologues and 1 paralogue. Broad expression in testis (RPKM 10.6), thyroid (RPKM 2.4) and 19 other tissues.

Summary

Predicted to enable Myosin light chain binding activity. Predicted to be involved in motile cilium assembly and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in sperm connecting piece. [provided by Alliance of Genome Resources, Apr 2022]

SPATA6 Products(3)

mRNA Protein Name
NM_001286238.2 NP_001273167.1 spermatogenesis-associated protein 6 isoform 2
NM_001286239.2 NP_001273168.1 spermatogenesis-associated protein 6 isoform 3
NM_019073.4 NP_061946.1 spermatogenesis-associated protein 6 isoform 1 precursor

SPATA6 Protein Structure

SPATA6

SPATA6: Spermatogenesis-assoc protein 6 (11 - 149)

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  • 488 a.a.
Protein Preferred Names Protein Names

spermatogenesis-associated protein 6

spermatogenesis-related factor-1

Related Diseases

Diseases Alias
Spermatogenic Failure 16

SPGF16

Acephalic Spermatozoa Syndrome

Spermatozoa, Acephalic
Male Infertility Due To Acephalic Spermatozoa

Acephalic Spermatozoa Syndrome
Myopathy, Areflexia, Respiratory Distress, And Dysphagia, Early-Onset

EMARDD

Myopathy, Areflexia, Respiratory Distress, And Dysphagia, Early-Onset, Mild Variant

Early-Onset Myopathy-Areflexia-Respiratory Distress-Dysphagia Syndrome

Early-Onset Myopathy, Areflexia, Respiratory Distress And Dysphagia

Myopathy, Early-Onset, Areflexia, Respiratory Distress, And Dysphagia
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13643 SPATA6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SPATA6 VGNC VGNC:77953
Felis catus SPATA6 VGNC VGNC:65617
Rattus norvegicus SPATA6 RGD RGD:628657
Bos taurus SPATA6 VGNC VGNC:35189
Canis familiaris SPATA6 VGNC VGNC:46717
Mus musculus SPATA6 MGD MGI:1915196