2. Gene
  3. ZWILCH - zwilch kinetochore protein Gene

ZWILCH - zwilch kinetochore protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KNTC1AP; hZwilch

Gene ID: 55055 | Gene type: protein coding

About ZWILCH

Cytogenetic location: 15q22.31 Genomic coordinates (GRCh38): 15:66,505,326-66,550,130 (from NCBI)

This gene has 14 transcripts (splice variants) and 197 orthologues. Broad expression in testis (RPKM 32.5), lymph node (RPKM 6.0) and 19 other tissues.

Summary

Involved in protein localization to kinetochore. Located in kinetochore. Part of RZZ complex. [provided by Alliance of Genome Resources, Apr 2022]

ZWILCH Products(4)

mRNA Protein Name
NM_001287821.2 NP_001274750.1 protein zwilch homolog isoform 2
NM_001287822.2 NP_001274751.1 protein zwilch homolog isoform 2
NM_001287823.2 NP_001274752.1 protein zwilch homolog isoform 2
NM_017975.5 NP_060445.3 protein zwilch homolog isoform 1

ZWILCH Protein Structure

Zwilch

Zwilch: RZZ complex, subunit zwilch (31 - 587)

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  • 591 a.a.
Protein Preferred Names Protein Names

protein zwilch homolog

Zwilch, kinetochore associated, homolog

Related Diseases

Diseases Alias
Chondrodysplasia With Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia

X-Linked Dominant Chondrodysplasia, Chassaing-Lacombe Type

X-Linked Dominant Chondrodysplasia-Hydrocephaly-Microphthalmia Syndrome

CDP-PBHM

Chondrodysplasia, With Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia
Mosaic Variegated Aneuploidy Syndrome

Warburton-Anyane-Yeboa Syndrome

Mva Syndrome

Mosaic Variegated Aneuplody Microcephaly Syndrome

Warburton Anyane Yeboa Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16209 ZWILCH Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZWILCH RGD RGD:1583880
Felis catus ZWILCH VGNC VGNC:67389
Bos taurus ZWILCH VGNC VGNC:37391
Macaca mulatta ZWILCH VGNC VGNC:79496
Canis familiaris ZWILCH VGNC VGNC:48865
Mus musculus ZWILCH MGD MGI:1915264