SLC6A15 - solute carrier family 6 member 15 Gene

Homo sapiens

Also known as V7-3; NTT73; SBAT1; hv7-3

Gene ID: 55117 | Gene type: protein coding

About SLC6A15

Cytogenetic location: 12q21.31 Genomic coordinates (GRCh38): 12:84,859,491-84,912,799 (from NCBI)

This gene has 45 transcripts (splice variants), 219 orthologues and 19 paralogues. Biased expression in brain (RPKM 5.0), placenta (RPKM 1.2) and 3 other tissues.

Summary

This gene encodes a member of the solute carrier family 6 protein family which transports neutral Amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

SLC6A15 Products(3)

mRNA	Protein	Name
NM_001146335.3	NP_001139807.1	sodium-dependent neutral amino acid transporter B(0)AT2 isoform 3
NM_018057.7	NP_060527.2	sodium-dependent neutral amino acid transporter B(0)AT2 isoform 2
NM_182767.6	NP_877499.1	sodium-dependent neutral amino acid transporter B(0)AT2 isoform 1

SLC6A15 Protein Structure

SNF

0
200
400
600
730 a.a.

Protein Preferred Names

Protein Names

sodium-dependent neutral amino acid transporter B(0)AT2

homolog of rat orphan transporter v7-3

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 3

Epileptic Encephalopathy, Early Infantile, 3	DEE3
Eiee3	Early Myoclonic Encephalopathy
Developmental And Epileptic Encephalopathy, 3	Early Infantile Epileptic Encephalopathy 3
Eme	Neonatal Epilepsy With Suppression-Burst Pattern
Encephalopathy, Epileptic, Early Infantile, Type 3

Hartnup Disorder

Hartnup Disease	HND
Neutral 1 Amino Acid Transport Defect	Neutral Amino Acid Transport Defect
Deficiency Of Tryptophan Oxygenase	Hartnup'S Disease
Aminoaciduria, Hartnup Type	Disorder Of Neutral Amino Acid Transport

Retinitis Pigmentosa 68

RP68	Retinitis Pigmentosa, Type 68

Iminoglycinuria

Iminoglycinuria, Digenic

Hyperekplexia

Hereditary Hyperekplexia	Kok Disease
Congenital Stiff Man Syndrome	Familial Startle Disease
Sthe	Stiff-Baby Syndrome
Hereditary Hyperexplexia	Startle Disease
Exaggerated Startle Reaction	Hyperexplexia Hereditary
Startle Disease, Familial	Startle Reaction, Exaggerated
Stiff-Man Syndrome, Congenital	Stiff-Person Syndrome, Congenital
Congenital Stiff-Man Syndrome	Congenital Stiff-Person Syndrome
Familial Hyperekplexia	Startle Syndrome
Stiff Baby Syndrome	Hyperekplexia, Hereditary
Stiff-Person Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13301	SLC6A15 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SLC6A15	RGD	RGD:628664
Mus musculus	SLC6A15	MGD	MGI:2143484
Felis catus	SLC6A15	VGNC	VGNC:65411
Canis familiaris	SLC6A15	VGNC	VGNC:46458
Bos taurus	SLC6A15	VGNC	VGNC:34918
Macaca mulatta	SLC6A15	VGNC	VGNC:77691

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