2. Gene
  3. PIWIL2 - piwi like RNA-mediated gene silencing 2 Gene

PIWIL2 - piwi like RNA-mediated gene silencing 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CT80; HILI; mili; PIWIL1L

Gene ID: 55124 | Gene type: protein coding

About PIWIL2

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,275,316-22,357,568 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 3 paralogues. Biased expression in testis (RPKM 18.7), duodenum (RPKM 3.2) and 2 other tissues.

Summary

PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]

PIWIL2 Products(3)

mRNA Protein Name
NM_001135721.3 NP_001129193.1 piwi-like protein 2 isoform 1
NM_001330480.2 NP_001317409.1 piwi-like protein 2 isoform 2
NM_018068.5 NP_060538.2 piwi-like protein 2 isoform 1

PIWIL2 Protein Structure

PAZ

PAZ: PAZ domain (390 - 524)

Piwi

Piwi: Piwi domain (668 - 956)

  • 0
  • 200
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  • 800
  • 973 a.a.
Protein Preferred Names Protein Names

piwi-like protein 2

cancer/testis antigen 80

Related Diseases

Diseases Alias
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
Infertility
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10585 PIWIL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PIWIL2 VGNC VGNC:44593
Macaca mulatta PIWIL2 VGNC VGNC:81502
Bos taurus PIWIL2 VGNC VGNC:32928
Felis catus PIWIL2 VGNC VGNC:79363
Mus musculus PIWIL2 MGD MGI:1930036
Rattus norvegicus PIWIL2 RGD RGD:1306964