1. Gene
  2. LSG1 - large 60S subunit nuclear export GTPase 1 Gene

LSG1 - large 60S subunit nuclear export GTPase 1 Gene

Homo sapiens
Gene ID: 55341 | Gene type: protein coding

About LSG1

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:194,640,791-194,672,191 (from NCBI)

This gene has 8 transcripts (splice variants), 208 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 9.7), thyroid (RPKM 9.6) and 25 other tissues.

Summary

This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb 2009]

LSG1 Products(1)

mRNA Protein Name
NM_018385.3 NP_060855.2 large subunit GTPase 1 homolog

LSG1 Protein Structure

MMR_HSR1

MMR_HSR1: 50S ribosome-binding GTPase (389 - 446)

  • 0
  • 200
  • 400
  • 600
  • 658 a.a.
Protein Preferred Names Protein Names

large subunit GTPase 1 homolog

hLsg1

Related Diseases

Diseases Alias
Shwachman-Diamond Syndrome 1

Shwachman-Diamond Syndrome

Shwachman Syndrome

Shwachman-Bodian-Diamond Syndrome

Sds

Pancreatic Insufficiency And Bone Marrow Dysfunction

Shwachman-Bodian Syndrome

SDS1

Lipomatosis Of Pancreas, Congenital

Congenital Lipomatosis Of Pancreas

Shwachman-Diamond Type Metaphyseal Dysplasia

Metaphyseal Chondrodysplasia, Shwachman Type

Shwachman-Diamond-Oski Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus LSG1 VGNC VGNC:31049
Rattus norvegicus LSG1 RGD RGD:1309089
Canis familiaris LSG1 VGNC VGNC:42837
Felis catus LSG1 VGNC VGNC:63321
Macaca mulatta LSG1 VGNC VGNC:74360
Mus musculus LSG1 MGD MGI:107236