TTC17 - tetratricopeptide repeat domain 17 Gene

Homo sapiens

Gene ID: 55761 | Gene type: protein coding

About TTC17

Cytogenetic location: 11p12-p11.2 Genomic coordinates (GRCh38): 11:43,358,920-43,494,931 (from NCBI)

This gene has 16 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in thyroid (RPKM 14.5), ovary (RPKM 10.5) and 25 other tissues.

Summary

Involved in actin filament polymerization and cilium organization. Located in actin cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TTC17 Products(6)

mRNA	Protein	Name
NM_001307943.2	NP_001294872.1	tetratricopeptide repeat protein 17 isoform 2
NM_001376525.1	NP_001363454.1	tetratricopeptide repeat protein 17 isoform 3
NM_001376526.1	NP_001363455.1	tetratricopeptide repeat protein 17 isoform 4
NM_001376527.1	NP_001363456.1	tetratricopeptide repeat protein 17 isoform 5
NM_001376528.1	NP_001363457.1	tetratricopeptide repeat protein 17 isoform 6
NM_018259.6	NP_060729.2	tetratricopeptide repeat protein 17 isoform 1

TTC17 Protein Structure

TPR_1

TPR_11

TPR_1

0
200
400
600
800
1000
1141 a.a.

Protein Preferred Names

Protein Names

tetratricopeptide repeat protein 17

TPR repeat protein 17

Related Diseases

Diseases

Alias

Pancreatic Squamous Cell Carcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15200	TTC17 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TTC17	RGD	RGD:1305410
Bos taurus	TTC17	VGNC	VGNC:36457
Mus musculus	TTC17	MGD	MGI:1921819
Felis catus	TTC17	VGNC	VGNC:66654
Canis familiaris	TTC17	VGNC	VGNC:47940
Macaca mulatta	TTC17	VGNC	VGNC:79516

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