PAG1 - phosphoprotein membrane anchor with glycosphingolipid microdomains 1 Gene

Homo sapiens

Also known as CBP; PAG

Gene ID: 55824 | Gene type: protein coding

About PAG1

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:80,967,810-81,112,068 (from NCBI)

This gene has 4 transcripts (splice variants) and 193 orthologues. Broad expression in lymph node (RPKM 8.7), placenta (RPKM 8.2) and 25 other tissues.

Summary

The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq, Jul 2008]

PAG1 Products(1)

mRNA	Protein	Name
NM_018440.4	NP_060910.3	phosphoprotein associated with glycosphingolipid-enriched microdomains 1

PAG1 Protein Structure

PAG

0
100
200
300
400
432 a.a.

Protein Preferred Names

Protein Names

phosphoprotein associated with glycosphingolipid-enriched microdomains 1

Csk-binding protein

Related Diseases

Diseases

Alias

Chromosome 8q21.11 Deletion Syndrome

8q21.11 Microdeletion Syndrome	Del(8)(Q21.11)
Deletion 8q21.11	Monosomy 8q21.11

B-Lymphoblastic Leukemia/Lymphoma With Hypodiploidy

B-All With Hypodiploidy

Hypodiploid All

Peters-Plus Syndrome

Krause-Kivlin Syndrome	Peters Plus Syndrome
Peters Anomaly	Irido-Corneo-Trabecular Dysgenesis
PTRPLS	Peters Anomaly With Short-Limb Dwarfism
Peters Anomaly-Short Limb Dwarfism Syndrome	Peters Anomaly With Short Limb Dwarfism
Peters Congenital Glaucoma	Krause-Van Schooneveld-Kivlin Syndrome
Peters' Plus Syndrome	Peters'-Plus Syndrome
Anomaly Peters

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09971	PAG1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PAG1	VGNC	VGNC:32553
Felis catus	PAG1	VGNC	VGNC:64025
Rattus norvegicus	PAG1	RGD	RGD:620394
Canis familiaris	PAG1	VGNC	VGNC:44242
Mus musculus	PAG1	MGD	MGI:2443160
Macaca mulatta	PAG1	VGNC	VGNC:75698
Others	PAG1	NCBI