SLC39A10 - solute carrier family 39 member 10 Gene

Homo sapiens

Also known as ZIP10; LZT-Hs2

Gene ID: 57181 | Gene type: protein coding

About SLC39A10

Cytogenetic location: 2q32.3 Genomic coordinates (GRCh38): 2:195,613,029-195,737,700 (from NCBI)

This gene has 9 transcripts (splice variants), 185 orthologues and 6 paralogues. Broad expression in thyroid (RPKM 12.9), brain (RPKM 12.5) and 21 other tissues.

Summary

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

SLC39A10 Products(2)

mRNA	Protein	Name
NM_001127257.2	NP_001120729.1	zinc transporter ZIP10 precursor
NM_020342.3	NP_065075.1	zinc transporter ZIP10 precursor

SLC39A10 Protein Structure

Zip

0
200
400
600
831 a.a.

Protein Preferred Names

Protein Names

zinc transporter ZIP10

ZIP-10

Related Diseases

Diseases

Alias

Acrodermatitis Enteropathica, Zinc-Deficiency Type

Acrodermatitis Enteropathica	AEZ
Enteropathica	Brandt Syndrome
Ae	Acrodermatitis Enteropathica Zinc Deficiency Type
Danbolt-Cross Syndrome	Acrodermatitis Enteropathica, Zinc Deficiency Type
Inherited Zinc Deficiency	Acrodermatitis Enteropathica, Zinc Deficiency
Danbolt-Closs Syndrome	Primary Zinc Malabsorption Syndrome

Ehlers-Danlos Syndrome, Spondylodysplastic Type, 3

Spondylocheirodysplasia, Ehlers-Danlos Syndrome-Like	Scd-Eds
EDSSPD3	Ehlers-Danlos Syndrome Spondylodysplastic Type 3
Ehlers-Danlos Syndrome, Spondylocheirodysplastic Type	Slc39a13-Related Spondylodysplastic Ehlers-Danlos Syndrome
Slc39a13-Related Speds	Slc39a13-Related Spondylodysplastic Eds
Spondylocheirodysplastic Ehlers-Danlos Syndrome	Speds-Slc39a13
Ehlers-Danlos Syndrome-Like Spondylocheirodysplasia	Ehlers-Danlos Syndrome, Spondylodysplastic, Type 3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13229	SLC39A10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC39A10	VGNC	VGNC:65354
Bos taurus	SLC39A10	VGNC	VGNC:34858
Macaca mulatta	SLC39A10	VGNC	VGNC:77540
Mus musculus	SLC39A10	MGD	MGI:1914515
Rattus norvegicus	SLC39A10	RGD	RGD:1307321
Canis familiaris	SLC39A10	VGNC	VGNC:57394

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