KAT14 - lysine acetyltransferase 14 Gene

Homo sapiens

Also known as ATAC2; CRP2BP; CSRP2BP; PRO1194; dJ717M23.1

Gene ID: 57325 | Gene type: protein coding

About KAT14

Cytogenetic location: 20p11.23 Genomic coordinates (GRCh38): 20:18,137,153-18,188,372 (from NCBI)

This gene has 13 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in brain (RPKM 8.7), testis (RPKM 8.1) and 25 other tissues.

Summary

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

KAT14 Products(15)

mRNA	Protein	Name
NM_001384192.3	NP_001371121.2	cysteine-rich protein 2-binding protein isoform 1
NM_001392069.1	NP_001378998.1	cysteine-rich protein 2-binding protein isoform 1
NM_001392070.1	NP_001378999.1	cysteine-rich protein 2-binding protein isoform 1
NM_001392071.1	NP_001379000.1	cysteine-rich protein 2-binding protein isoform 1
NM_001392072.1	NP_001379001.1	cysteine-rich protein 2-binding protein isoform 1
NM_001392073.1	NP_001379002.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392074.1	NP_001379003.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392075.1	NP_001379004.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392076.1	NP_001379005.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392077.1	NP_001379006.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392078.1	NP_001379007.1	cysteine-rich protein 2-binding protein isoform 2
NM_001392079.1	NP_001379008.1	cysteine-rich protein 2-binding protein isoform 3
NM_001392080.1	NP_001379009.1	cysteine-rich protein 2-binding protein isoform 4
NM_001392081.1	NP_001379010.1	cysteine-rich protein 2-binding protein isoform 5
NM_020536.7	NP_065397.4	cysteine-rich protein 2-binding protein isoform 1

KAT14 Protein Structure

Acetyltransf_1

0
200
400
600
782 a.a.

Protein Preferred Names

Protein Names

cysteine-rich protein 2-binding protein

ADA2A-containing complex subunit 2

Related Diseases

Diseases

Alias

Mitochondrial Complex Iv Deficiency, Nuclear Type 19

MC4DN19

Mitochondrial Complex 4 Deficiency, Nuclear Type 19

Buruli Ulcer

Buruli Ulcer, Susceptibility To	Buruli Ulcer Disease
Mycobacterium Ulcerans	Mycobacterium Ulcerans, Susceptibility To
Bairnsdale Ulcer	Daintree Ulcer
Mossman Ulcer	Searl Ulcer
Searle'S Ulcer	Bud

Filippi Syndrome

Scott Craniodigital Syndrome With Mental Retardation	Type 1 Syndactyly-Microcephaly-Intellectual Disability Syndrome
FLPIS	Scott Bryant Graham Syndrome
Craniodigital-Intellectual Disability Syndrome	Scott Craniodigital Syndrome
Scott-Bryant-Graham Syndrome	Syndactyly, Type I, With Microcephaly And Mental Retardation
Syndactyly Type I With Microcephaly And Intellectual Disability	Unusual Facial Appearance, Microcephaly, Growth And Intellectual Disability And Syndactyly
Craniodigital Syndrome With Intellectual Disability	Craniodigital Syndrome-Intellectual Disability Syndrome
Craniodigital Syndrome-Intellectual Disability, Scott Type	Intellectual Disability-Craniodigital Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07073	KAT14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KAT14	RGD	RGD:1309538
Bos taurus	KAT14	VGNC	VGNC:30397
Felis catus	KAT14	VGNC	VGNC:63022
Mus musculus	KAT14	MGD	MGI:1917264
Canis familiaris	KAT14	VGNC	VGNC:42208

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