PLAAT4 - phospholipase A and acyltransferase 4 Gene

Homo sapiens

Also known as RIG1; TIG3; HRSL4; HRASLS4; PLAAT-4; RARRES3; PLA1/2-3

Gene ID: 5920 | Gene type: protein coding

About PLAAT4

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:63,536,808-63,546,458 (from NCBI)

This gene has 5 transcripts (splice variants), 73 orthologues and 7 paralogues. Ubiquitous expression in small intestine (RPKM 43.2), duodenum (RPKM 36.6) and 24 other tissues.

Summary

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear Receptor Proteins that are members of the steroid and Thyroid Hormone Receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]

PLAAT4 Products(1)

mRNA	Protein	Name
NM_004585.5	NP_004576.2	phospholipase A and acyltransferase 4

PLAAT4 Protein Structure

LRAT

0
100
164 a.a.

Protein Preferred Names

Protein Names

phospholipase A and acyltransferase 4

HRAS-like suppressor 4

Related Diseases

Diseases

Alias

Exocervical Carcinoma

Carcinoma Of Exocervix

Carcinoma Of The Exocervix

Poland Syndrome

Poland Anomaly	Poland Sequence
Poland Syndactyly	Poland'S Syndrome
Poland'S Anomaly	Poland'S Syndactyly
Acro-Pectoro-Renal Field Defect	Brachydactyly, Absent Pectoral Muscles And Agenesis/Hypoplasia Of Kidneys
Unilateral Defect Of Pectoralis Muscle And Syndactyly Of The Hand	Unilateral Defect Of Pectoralis Major And Syndactyly Of The Hand

Psoriasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10639	PLAAT4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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